摘要
声波可以非接触、无损伤地操控微粒,其在细胞操纵、材料组装等领域具有广阔的应用前景.然而,如何高通量、灵活且快速操控微粒仍然面临挑战.在本工作中,利用二维声子晶体板的周期局域梯度场实现了大规模微粒的并行操控.其主要机制是由于黄铜平板刻蚀周期分布的正方体凸起构成的二维声子晶体板可激发板子固有的Lamb波零阶反对称模式;其周期局域梯度场在平行于声子晶体板表面为驻波声场、在垂直于声子晶体板表面为局域梯度声场;该周期分布的局域声场可以对微粒产生平行于表面的声停驻力、垂直于表面的声吸引力.我们进一步构建了操控实验装置,利用压电陶瓷片激励二维声子晶体板,在实验中观察到了玻璃微球的捕获和排列现象,实现了大规模微粒的二维排列操控.该工作为高通量、快速、灵活操控微粒和细胞等提供了物理基础和技术支持.
Acoustic waves can manipulate particles without contact or damage,and has received increasing attention due to their potential applications in various fields,such as cell sorting,organoid construction,and material assembly.In general,high-throughput manipulation of microparticles relies on a large number of active transducers and phase-shifting circuits to create standing wave patterns,thus significantly inducing system complexity.Recently,we realized the parallel manipulation of microparticles by using an acoustic field modulated by a one-dimensional phononic crystal plate.The concept is based on the fact that phononic crystal plate can resonantly excite the zero-order asymmetric(A_0)Lamb wave,inducing highly localized periodic radiation force on the particles.In this paper,we further show that by using a two-dimensional phononic crystal plate(TDPCP),parallel manipulation of massive particles can be achieved only with a single transducer.The A_(0)Lamb wave can be excited by a TDPCP,forming a two-dimensional periodic localized field,and then particles can suffer negative vertical force and stable zero horizontal force,inducing two-dimensional periodic trapping on the surface of the plate.Combining a PZT source with a TDPCP consisting of a brass plate patterned with periodical brass stubs,we observe the capture and arrangement of glass microspheres,achieving two-dimensional arrangement manipulation of particles on the TDPCP.This system represents a significant advancement in developing high-throughput,rapid,and flexible devices for particles and cell manipulation.
作者
王燕萍
蔡飞燕
李飞
张汝钧
李永川
王金萍
张欣
郑海荣
Wang Yan-Ping;Cai Fei-Yan;Li Fei;Zhang Ru-Jun;Li Yong-Chuan;Wang Jin-Ping;Zhang Xin;Zheng Hai-Rong(Department of Physics and Optoelectric Engineering,Guangdong University of Technology,Guangzhou 510006,China;Paul C.Lauterbur Research Center for Biomedical Imaging,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China)
出处
《物理学报》
SCIE
EI
CAS
CSCD
北大核心
2023年第14期131-136,共6页
Acta Physica Sinica
基金
国家自然科学基金(批准号:12004409,11974372,12004408,12274095)
深圳市科技计划(批准号:RCJC20221008092808013,JCYJ20200109105823170,JCYJ20200109110006136)资助的课题。
关键词
声子晶体
声辐射力
微粒操控
phononic crystal
acoustic radiation force
particle manipulation
