摘要
目的探讨三球仪与踏车运动相联合的方案治疗稳定期慢性阻塞性肺疾病(COPD)患者临床效果。方法选取2021年8月至2022年8月我院收治的稳定期COPD患者80例,采用随机数字表法分成两组各40例,A组给予常规药物(吸入)治疗,B组在A组基础上开展三球仪+踏车运动治疗。比较两组临床疗效,肺功能指标如肺活量(VC)、用力肺活量(FVC)与1s用力呼气量(FEV_(1))、运动耐力6分钟步行距离(6MWD),炎性细胞因子指标白介素(IL)-1、IL-6、肿瘤坏死因子(TNF-α),采用呼吸困难量表(mMRC)评定两组呼吸困难程度。结果B组治疗总有效率97.50%明显高于A组80.00%(P<0.05);B组治疗3个月时的VC、FEV_(1)与FVC均高于A组,IL-1、IL-6、TNF-α均低于A组(P<0.05);B组治疗后6MWD长于A组(P<0.05),mMRC评分低于A组低(P<0.05)。结论针对稳定期COPD患者,通过给予踏车运动与三球仪相联合的方案来实施治疗,临床效果好,能显著改善其肺功能与呼吸困难情况,降低炎性细胞因子水平,提高运动耐力。
Objective To explore the clinical effect of three-ball instrument and treadmill exercise in the treatment of patients with stable chronic obstructive pulmonary disease(COPD).Methods Eighty patients with stable COPD admitted to our hospital from August 2021 to August 2022 were selected.The patients were divided into group A and B according to random number method,40 in each group.The group A was treated with conventional drugs(inhalation).The group B was treated with three-ball instrument+treadmill exercise on the basis of the group A.The clinical effects,lung function indexes such as vital capacity(VC),forced vital capacity(FVC)and forced expiratory volume(FEV1)in 1s,exercise endurance(6-minute walking distance,6MWD),inflammatory cytokine indexes such as interleukin(IL)-1,IL-6,and tumor necrosis factor(TNF-α)were compared between the two groups.The dyspnea scale(mMRC)was used to assess the degree of dyspnea in the two groups.Results The total effective rate of the group B was 9750%,which was significantly higher than 8000%of the group A(P<0.05).After 3 months of treatment,VC,FEV_(1)and FVC in the group B were higher than those in the group A,and the levels of IL-1,IL-6 and TNF-αin the group B were lower than those in the group A(P<0.05).After treatment,the 6MWD of the group B was longer than that of the group A(P<0.05).The mMRC score of the group B was lower than that of the group A(P<0.05).Conclusions For patients with stable COPD,the combination of treadmill exercise and three-ball instrument have a good clinical effect.It can significantly improve their lung function and dyspnea,reduce the level of inflammatory cytokines,and improve the exercise endurance.
作者
罗秀琼
张燕
陶丽
朱克鹏
陈艳
LUO Xiu-qiong;ZHANG Yan;TAO Li;ZHU Ke-peng;CHEN Yan(Department of Respiratory and Critical Care Medicine,Nanchong Center Hospital,Nanchong 637000,China;Department of Pharmacy,Nanchong Center Hospital,Nanchong 637000,China;Department of Rehabilitation,Nanchong Center Hospital,Nanchong 637000,China;Department of Breast and Thyroid Vascular Surgery,Nanchong Center Hospital,Nanchong 637000,China)
出处
《实用医院临床杂志》
2023年第4期90-94,共5页
Practical Journal of Clinical Medicine
基金
四川省医学会科研基金资助项目(编号:Q21068)
南充市科学技术与知识产权局科研基金资助项目(编号:18YFZJ0020)
名老中医医案研究中心科研基金资助项目(编号:YAZX19-Y-01)。
关键词
慢性阻塞性肺疾病
稳定期
三球仪
踏车运动
运动耐力
呼吸困难
Chronic obstructive pulmonary disease
Stable period
Three ball instrument
Bicycle sports
Sports endurance
Dyspnea
