摘要
神经系统是介导针刺效应的必要条件,而交感神经/迷走神经广泛分布于全身,将人体各系统器官有机地联络起来,在维持人体生理活动协调统一上符合针刺调节的整体观、双向性,并与“内属脏腑,外络肢节”的经络理论相契合。针刺作为一种体表刺激疗法,通过兴奋交感神经/迷走神经介导的多种抗炎通路,抑制机体炎性反应。不同穴位下的外周神经决定了自主神经抗炎效应途径的差异,而不同针法(刺激形式和刺激量)是影响自主神经抗炎机制的重要因素。今后应从脑神经环路层面解析针刺调控交感神经和迷走神经间的中枢整合机制,明确针刺的“多靶点”优势,以期为针刺神经-免疫学机制研究提供启示与借鉴。
The nervous system is the necessary condition for inducing the curative effect of acupuncture.Both the sympathetic and vagal nerve systems are widely distributed throughout the body and organically connect various systems and organs of the human body.In maintaining the coordination and unity of human physiological activities,it is in line with the holistic view and bidirectional regulation of acupuncture,and fits in with the meridian theory of“internally belonging to the Zang-fu organs and externally connecting with the limbs and joints”.Acupuncture,one of the body surface stimulation therapies,can inhibit the inflammatory response via activating sympathetic/vagus nerve mediated anti-inflammatory pathways.The peripheral nerve innervating diffe-rent acupoints determines the different anti-inflammatory pathways of the autonomic nerve,and different acupuncture methods(stimulation form and stimulation amount)are important factors affecting the anti-inflammatory mechanism of the autonomic nerve.In the future,we should analyze the central integration mechanism between sympathetic nerve and vagus nerve regulated by acupuncture at the level of brain neural circuits,and clarify the“multi-target”advantage of acupuncture,so as to provide inspiration and reference for the study of neuroimmunological effects of acupuncture.
作者
杨娜娜
马欣
李月婕
杨静雯
李洪萍
张宇沁
刘存志
YANG Na-na;MA Xin;LI Yue-jie;YANG Jing-wen;LI Hong-ping;ZHANG Yu-qin;LIU Cun-zhi(School of Acu-puncture-moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China;College of Acupuncture and Massage,Shandong University of Traditional Chinese Medicine,Jinan 250300)
出处
《针刺研究》
CAS
CSCD
北大核心
2023年第6期610-617,共8页
Acupuncture Research
基金
国家杰出青年科学基金项目(No.818251124)
国家重点研发计划项目(No.2019YFC1712104)。
关键词
针刺
抗炎
自主神经
脑神经环路
Acupuncture
Anti-inflammation
Autonomic nerve
Brain nerve circuit
