摘要
目的评估房颤患者在风险条件下的决策能力。方法选取房颤患者31例作为研究对象,与其性别、年龄相匹配的健康人群志愿者32例作为对照组,分别进行骰子博弈测试(Game of dice test,GDT)、简易精神状态检查(Mini-mental state examination,MMSE)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、汉密尔顿抑郁量表(Hamilton depression scale-17,HAMD-17)、连线测验(Trail making test,TMT)、词汇流畅性测验(Verbal fluency test,VFT)、数字广度测试(Digit span test,DST)、符号-数字模式测验(Symbol digit modalities test,SDMT)评定,明确房颤组风险决策能力是否受损并进行相关因素分析。GDT评估指标包括(1)最终资本;(2)选择4种不同选项的频次;(3)总体净得分和风险得分;(4)负反馈利用率。结果房颤组最终资本低于健康对照组,但2组比较无明显差异(P>0.05)。房颤组4个数字选择次数、总体净得分显著低于健康对照组(t=-2.465,-2.073,P<0.05),风险得分显著高于健康对照组(t=2.696,P<0.05)。相关性分析显示最终资本与TMT-B得分呈负相关(r=-0.364,P=0.044),3个数字选择次数、总体净得分、负反馈利用率与DST-f得分呈正相关(r>0.360,P<0.05),4个数字选择次数与年龄呈正相关(r=0.403,P=0.025)。结论房颤患者风险条件下的决策能力受损,其与年龄、执行功能、工作记忆有关。
Objective To evaluate decision making under risk conditions and related factors in patients with AF.Methods 31 patients with AF were selected as the research objects,and 32 healthy volunteers matched with their gender and age were selected as the control group.The performance of game of dice test(GDT),mini-mental state examination(MMSE),Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD-17),trail making test(TMT),verbal fluency test(VFT),digit span test(DST),and symbol digit modalities test(SDMT)were compared between the two groups,and related factors were analyzed.GDT evaluation indicators include:(1)Final capital;(2)Frequency of selecting four different options;(3)Overall net score and risk score;(4)Negative feedback utilization rate.Results The final capital of the AF group was lower than that of the control group,but there was no statistically significant difference between the two groups(P>0.05).The frequency of four numbers and overall net score in AF group were significantly lower than those in control group(t=-2.465,-2.073,P<0.05),and the risk score was significantly higher than that in control group(t=2.696,P<0.05).Correlation analysis showed that final capital was negatively correlated with TMT-B scores.The frequency of three numbers,overall net score and negative feedback utilization were positively correlated with DST-F score,and the frequency of four numbers were positively correlated with age.Conclusion The decision-making under risk of AF patients is impaired,which is related to age,executive function and working memory.
作者
吕龙琴
毛善平
Lv Longqin;Mao Shanping(Department of Neurology,Renmin Hospital of Wuhan University,Wuhan 430060)
出处
《卒中与神经疾病》
2023年第3期302-306,共5页
Stroke and Nervous Diseases
基金
湖北省卫健委面上项目(编号为WJ2019M189)
关键词
风险条件下的决策
房颤
骰子博弈测试
Atrial fibrillation
Decision-making under risk
Game of dice test(GDT)
