摘要
目的:分析磁共振成像(MRI)结合颈动脉超声定量参数在老年急性脑梗死(ACI)致血管性痴呆(VD)患者病情及疗效评估中的应用价值。方法:选取2021年1月至2022年7月珠海市第五人民医院及南方医科大学附属珠江医院收治的老年ACI患者共计120例,均行MRI结合颈动脉超声检查,根据是否合并VD,分为非VD组(21例)和VD组(99例);治疗前,根据临床痴呆评定量表将VD组患者分为轻度组、中度组及重度组,分别为32例、41例、26例;治疗后,根据疗效将VD组患者分为有效组(89例)和无效组(10例)。比较各组颈动脉超声参数[颈动脉内膜中层厚度(IMT)、颈内动脉收缩期峰值血流速度(PSV)、舒张末期流速(EDV)]及MRI相关参数[脑室和脑裂各项宽度、脑白质扩散系数(ADC)]。结果:四组患者治疗前IMT比较情况:非VD组<轻度组<中度组<重度组;PSV、EDV比较情况:非VD组>轻度组>中度组>重度组;四组患者治疗前脑室、脑裂各项宽度比较情况:非VD组>轻度组>中度组>重度组;ADC比较情况:非VD组<轻度组<中度组<重度组,组间差异均具有统计学意义(P<0.05)。有效组IMT明显小于无效组,PSV、EDV明显大于无效组,差异均具有统计学意义(P<0.05);有效组脑室、脑裂各项宽度明显大于无效组,ADC明显小于无效组,差异均具有统计学意义(P<0.05)。结论:MRI结合颈动脉超声定量参数可有效评估老年ACI致VD患者病情程度及疗效,指导临床制定早期干预措施。
Objective To analyze the application value of magnetic resonance imaging(MRI)combined with carotid artery ultrasound quantitative parameters in the evaluation of the condition and efficacy of elderly patients with acute cerebral infarction(ACI)-induced vascular dementia(VD).Methods A total of 120 elderly patients with acute cerebral infarction who were admitted to Zhuhai Fifth People's Hospital and ZhuJiang Hospital of Southern Medical University from January 2021 to July 2022 were selected,and all underwent MRI combined with carotid ultrasound examination,divided into non-VD group(21 cases)and VD group(99 cases);before treatment,patients in VD group were divided into mild group,moderate group and severe group according to the clinical dementia rating scale,with 32 cases,41 cases,and 26 cases,respectively.After treatment,the patients in VD group were divided into the effective group(89 cases)and the ineffective group(10 cases)according to the curative effect.The carotid ultrasound parameters[carotid intima-media thickness(IMT),internal carotid artery peak systolic blood flow velocity(PSV),end-diastolic flow velocity(EDV)]and MRI-related parameters[width of ventricle and schisis,white matter apparent diffusion coefficient(ADC)]were compared between groups.Results IMT comparison before treatment:non-VD group<mild group<moderate group<severe group;comparison of PSV and EDV:non-VD group>mild group>moderate group>severe group,the differences between the groups were statistically significant(P<0.05);comparison of the width of ventricle and schizophrenia before treatment:non-VD group>mild group>moderate group>severe group;ADC comparison:non-VD group<mild group<moderate group<severe group,the differences were statistically significant(P<0.05).After treatment,IMT in the effective group was significantly smaller than that in the ineffective group;PSV and EDV were significantly greater than those in the ineffective group(P<0.05);the width of ventricles,schizophrenia,and schizophrenia in the effective group were significantl
作者
揭育添
林波淼
吴莹
谢丽玲
黄裕存
黄胜福
JIE Yu-tian;LIN Bo-miao;WU Ying;XIE Li-ling;HUANG Yu-cun;HUANG Sheng-fu(Zhuhai Fifth People's Hospital,Guangdong Zhuhai 519000;Zhujiang Hospital of Southern Medical University,Guangdong Guangzhou 510280)
出处
《深圳中西医结合杂志》
2023年第9期5-8,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金
珠海市社会发展领域科技计划医疗卫生项目(2220004000292)。
关键词
急性脑梗死
血管性痴呆
磁共振成像
颈动脉超声
老年人
Acute cerebral infarction
Vascular dementia
Magnetic resonance imaging
Carotid ultrasound
Elderly people
