摘要
随着部分恶性肿瘤发病率的增长,使化疗药物被频繁使用,但化疗相关性肝损伤(CALI)却常常不受重视。化疗后药物性肝损伤的发生常常影响肿瘤治疗的效果,甚至使病情进展恶化。由于其诊断尚无统一、公认的标准,给损伤的早期诊断、早期治疗带来很大的难题。本文主要对化疗后药物性肝损伤的分型、损伤模式、临床表现、影响因素进行综述。
With the increase of the incidence of some malignant tumors,chemotherapeutic drugs are frequently used,but chemotherapy associated liver injury(CALI)after chemotherapy is often ignored.The occurrence of drug-induced liver injury after chemotherapy often affects the efficacy of tumor treatment,and even worsens the disease.Because there is no unified and recognized standard for its diagnosis,it brings great problems to the early diagnosis and treatment of injury.This article mainly reviews the classification,injury mode,clinical manifestation and influencing factors of drug-induced liver injury after chemotherapy.
作者
莫楚君
马金誉
缪辉来
MO Chujun;MA Jinyu;MIAO Huilai(Guangdong Medical University,Zhanjiang 524002,China)
出处
《中国医学创新》
CAS
2023年第18期166-169,共4页
Medical Innovation of China
基金
国家自然科学基金面上项目(82070637)
广东医科大学附属医院登峰计划项目(608DFY20190167)。
关键词
化疗
药物性肝损伤
急性肝衰竭
Chemotherapy
Drug-induced liver injury
Acute hepatic failure
