摘要
目的观察针刺治疗对急性胃肠损伤(AGI)危重症患者的血清脂肪酶(LPS)、二胺氧化酶(DAO)、肠脂肪酸结合蛋白(I-FABP)水平的影响。方法将64例患者按照随机数字表法随机分成两组,常规组32例,给予西医抗炎、抑酸护胃常规治疗;针刺组32例,在常规治疗基础上予针刺治疗,疗程为7 d。两组均在治疗第1、4、7天采集静脉血,采用ELISA法检测血清LPS、DAO、I-FABP的水平,比较两组患者在治疗第1、4和7天LPS、DAO、I-FABP的变化。结果治疗第1天,两组各项指标间比较无显著差异(P>0.05)。治疗第4、7天,针刺组的LPS、DAO、I-FABP均较常规组下降明显(P<0.05)。结论针刺联合常规西医治疗,可明显降低LPS、DAO、I-FABP水平,可能通过改善LPS、DAO、I-FABP水平促进肠康复。
Objective To observe the effect of acupuncture on the levels of serum lipase(LPS),diamine oxidase(DAO)and intestinal fatty acid-binding protein(I-FABP)in critically ill patients with acute gastrointestinal injury(AGI).Methods The 64 patients were randomly divided into two groups according to the random number table method.32 patients in the routine group were given conventional Western medicine treatment.In addition to the conventional group,32 patients in the acupuncture group received acupuncture treatment for 7 days.In the two groups,venous blood was collected on the 1st,4th,and 7th days of the treatment,and the levels of serum LPS,DAO,and I-FABP were detected by ELISA.The changes of LPS,DAO and I-FABP were compared between the two groups on the 1st,4th and 7th days of the treatment.Results On the first day of the treatment,there was no significant difference in the indicators between the two groups(P>0.05).On the 4th and 7th days of the treatment,the LPS,DAO and I-FABP of the acupuncture group were significantly lower than those of the conventional group(P<0.05).Conclusion Acupuncture combined with conventional western medicine treatment can significantly reduce the levels of LPS,DAO and I-FABP,which may promote intestinal rehabilitation by improving the levels of LPS,DAO and I-FABP.
出处
《浙江临床医学》
2023年第6期832-834,共3页
Zhejiang Clinical Medical Journal
基金
浙江省中医药科技计划项目(2020ZB257)。
