摘要
目的探讨肝癌患者术后发生下肢深静脉血栓的特征及其影响因素。方法收集2014年3月至2022年12月于中山市小榄人民医院接受手术治疗的60例肝癌患者的临床资料,根据术后是否发生下肢深静脉血栓并通过性别、年龄配对将其分为血栓组(n=30,术后住院期间发生下肢深静脉血栓)和对照组(n=30,术后住院期间未发生下肢深静脉血栓)。比较两组患者一般资料、手术指标以及围手术期药物治疗的差异,分析肝癌患者术后发生下肢深静脉血栓的特征及影响因素。结果血栓组患者慢性病发生率、凝血功能正常比例、术后止血药物使用率均高于对照组患者,差异均有统计学意义(P﹤0.05)。血栓组30例患者下肢深静脉血栓均在肝癌患者术后住院期间因下肢非对称性肿胀行下肢深静脉超声检查时发现,均为单侧下肢深静脉血栓,发病时间以术后1周内为主。结论肝癌患者术后下肢深静脉血栓形成主要发生于术后1周内,可能与患者的慢性病史、凝血功能情况以及术后使用止血药物有关。
Objective To investigate the characteristics and influencing factors of lower extremity deep venous thrombosis in patients with liver cancer after surgery.Method The clinical data of 60 patients with liver cancer who underwent surgical treatment in Xiaolan People's Hospital of Zhongshan from March 2014 to December 2022 were collected.They were divided into thrombosis group(n=30,lower extremity deep vein thrombosis occurred during postoperative hospitalization)and control group(n=30,no occurrence of postoperative lower extremity deep vein thrombosis during postoperative hospitalization)according to whether deep venous thrombosis of lower extremity occurred after the operation and matched by gender and age.The differences in the general data,surgical indicators,and perioperative medications of the two groups were compared.The characteristics and risk factors of postoperative deep venous thrombosis in patients with liver cancer were analyzed.Result The incidence of chronic diseases,the proportion of normal coagulation function,and the usage rate of postoperative hemostatic drugs in the thrombosis group were higher than those in the control group,the differences were statistically significant(P<0.05).The 30 cases of lower extremity deep venous thrombosis in the thrombosis group all experienced ultrasound examination of the lower extremity deep veins due to asymmetric swelling of the affected extremity during the postoperative hospitalization,the examination indicated that the above patients were all unilateral lower extremity deep venous thrombosis,and the onset time was mainly within 1 week after the surgery.Conclusion Postoperative deep venous thrombosis of lower extremity in patients with liver cancer mainly occurred within 1 week after surgery,which may be related to the patients'chronic medical history,blood coagulation function,and postoperative use of hemostatic drugs.
作者
关凯林
梁志宏
宋林泉
张风华
卢鑫
Guan Kailin;Liang Zhihong;Song Linquan;Zhang Fenghua;Lu Xin(Department of General Surgery,Xiaolan People's Hospital of Zhongshan,Zhongshan 528415,Guangdong,China;Department of Radiotherapy,Xiaolan People's Hospital of Zhongshan,Zhongshan 528415,Guangdong,China;Department of Interventional,Xiaolan People's Hospital of Zhongshan,Zhongshan 528415,Guangdong,China)
出处
《血管与腔内血管外科杂志》
2023年第5期612-615,共4页
Journal of Vascular and Endovascular Surgery
关键词
肝癌
手术
深静脉血栓
影响因素
liver cancer
surgery
deep vein thrombosis
influencing factor
