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阿立哌唑增效治疗难治性老年抑郁症临床效果及安全性分析

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摘要 目的分析阿立哌唑增效治疗难治性老年抑郁症临床效果及安全性。方法选取宝鸡市第二人民医院精神卫生科收治难治性老年抑郁症患者80例,按照治疗方案不同分为对照组与观察组,各40例。对照组使用常规抗抑郁药治疗,研究组在对照组基础上添加阿立哌唑治疗,比较两组患者治疗后的临床疗效及安全性。结果研究组治疗后抑郁评分为(9.48±1.33)、及焦虑评分为(8.67±2.25)分,较对照组明显改善(P<0.05);研究组较对照组不良反应发生率明显降低(5.00%vs20.00%)(P<0.05)。结论难治性老年抑郁症患者在文拉法辛基础上添加阿立哌唑治疗,可有效提高临床有效率,改善患者焦虑、抑郁状态,且安全性高。
作者 敬波 寇双双
出处 《当代临床医刊》 2023年第3期31-32,共2页 Journal of Contemporary Clinical Medicine
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