摘要
目的观察微针疗法联合超氧化物歧化酶(SOD)精华液和熊果苷精华液治疗黄褐斑的效果。方法 2019年9月至2021年6月, 中国医学科学院皮肤病医院整形美容科和南京江宁顾泽门诊部治疗面部黄褐斑患者80例, 男6例、女74例, 年龄28~48(37.3±4.9)岁。用微针疗法联合SOD精华液和熊果苷精华液综合治疗7次, 观察120 d。用改良黄褐斑面积及黄褐斑严重程度指数(mMASI)评分和治疗前后VISIA照片对比改善结果。结果 80例面部黄褐斑患者, 微针疗法治疗7次后(前5次每周1次, 9、10周做2次), 对比治疗前后照片并对患者面部黄褐斑mMASI评分进行统计学分析, 黄褐斑均有不同程度改善。治疗前, mMASI评分(5.4±3.2)分;90 d后, mMASI为(3.2±2.2)分, 评分显著下降(t=5.90, P<0.05)。120 d后, mMASI评分为(1.6±0.7)分, 评分再显著下降(t=7.55, P<0.05)。治疗中1例患者发生色素沉着, 修复治疗后色素沉着减退;无1例患者出现色素减退等不良反应。80例患者均有不同程度的毛孔及皮肤纹理改善。结论微针联合SOD精华液和熊果苷精华液治疗黄褐斑效果较好, 无明显不良反应, 为治疗黄褐斑提供了一个新方法。
Objective To observe the clinical efficacy of micro-needle therapy combined with Biotrisse BTS Lumin OX and Biotrisse BTS Brightline in the treatment of melasma.Methods From September 2019 to June 2021,80 patients with facial chloasma,aged 28-48(37.3±4.9)years,were selected from Nanjing Jiangning Guze Clinic.The micro-needle therapy was combined with lumin OX and brightline for 6 times,and the observation time was 120 days.The mMASI score and VISIA pho-tos before and after treatment were used to improve the results.Results Eighty patients with refrac-tory melasma on the face were treated with micro-needle therapy for 7 times(1 time per week for the first 5 times,and twice a week for the 9th and 1oth weeks).The photos before and after treatment were compared and the mMASI of the patients'facial chloasma was compared.The scores were ana-lyzed statistically,and the melasma were improved to varying degrees.Before treatment,the mMASI score was 5.4±3.22;90 days later,the mMASI was 3.22±2.16,and the score decreased signifi-cantly(t=5.9,P<0.05);after 120 days,mMASI score was 1.6±0.68,and the score decreased significantly(t=7.55,P<0.05).Pigmentation occurred in one patient after treatment,and hypop-igmentation after repair treatment;none of the patients had adverse reactions such as hypopigmenta-tion.All the 80 patients had different degrees of improvement in pores and skin texture.Conclusions The combination of micro-needling with lumin OX and brightline in the treatment of chloasma has a definite effect without obvious side effects.It provides a new method for the treatment of chloasma.
作者
张怡
赵小晖
赵金花
龚丹丹
刘浥
陈国富
Zhang Yi;Zhao Xiaohui;Zhao Jinhua;Gong Dandan;Liu Yi;Chen Guofu(Nanjing Institute of Dermatology,Chinese Academy of Medical Sciences/Peking Union Medical College,Nanjing 210042,China;Nanjing Jiangning Guze Clinic,Nanjing 211106,China)
出处
《中华医学美学美容杂志》
2023年第3期209-212,共4页
Chinese Journal of Medical Aesthetics and Cosmetology
