摘要
目的比较甲状腺腺叶全切术与甲状腺腺叶次全切除术治疗甲状腺结节的疗效及安全性。方法选取2019年1月至2021年1月本院收治的60例甲状腺结节患者作为研究对象,按信封法分为对照组和观察组,每组30例。观察组行甲状腺腺叶次全切除术治疗,对照组行甲状腺腺叶全切术治疗。比较两组临床疗效、手术指标(手术时间、术中出血量、术后住院时间、术后引流)、术后并发症发生情况及游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺激素(TSH)水平。结果观察组治疗总有效率为66.67%,明显低于对照组的90.00%,差异有统计学意义(P<0.05)。观察组手术时间、术后住院时间均短于对照组,术中出血量、术后引流量均少于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为10.00%,低于对照组的36.67%,差异有统计学意义(P<0.05)。术后,两组FT4水平均低于术前,观察组手术前后FT3、FT4水平比较差异无统计学意义,对照组FT3水平低于术前,TSH水平高于术前,且观察组FT3、FT4水平均高于对照组,TSH水平低于对照组,差异有统计学意义(P<0.05)。结论甲状腺腺叶全切术治疗甲状腺结节的临床疗效显著,但甲状腺腺叶次全切除术安全性更高,可减轻对甲状腺功能的损伤,两种治疗方式各有利弊,临床应结合患者实际情况选择最有益的手术方式。
Objective To compare the clinical efficacy and safety of total thyroidectomy and subtotal thyroidectomy in the treatmant thyroid nodule.Methods 60 patients with thyroid nodule admitted to our hospital from January 2019 to January 2021 were selected as research subjects,and they were divided into control group and observation group according to envelope method,with 30 casess in each group.The observation group was treated with subtotal thyroidectomy,and the control group was treated with total thyroidectomy.The clinical efficacy,surgical indexes(operation time,intraoperative blood loss,postoperative hospital stay,postoperative drainage),postoperative complications,and the levels of free triiodothyronine(FT3),free thyroxine(FT4)and thyroid stimulating hormone(TSH)were compared between the two groups.Results The total effective rate in the observation group was 66.67%,which was significantly lower than 90.00%in the control group,and the difference was statistically significant(P<0.05).The operation time and postoperative hospital stay in the observation group were shorter than those of the control group,and the intraoperative blood loss and postoperative drainage volume were less than those in the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was 10.00%,which was lower than 36.67%in the control group,and the difference was statistically significant(P<0.05).After surgery,FT4 level of both groups were lower than before surgery,there was no significant difference in FT3 and FT4 levels before and after operation in the observation group,FT3 level in the control group was lower than before surgery,and TSH level was higher than before surgery,and FT3 and FT4 levels in the observation group were higher than the control group,and TSH level was lower than the control group,the differences were statistically significant(P<0.05).Conclusion Total thyroidectomy of thyroid gland has significant clinical efficacy in the treatment of thyroid nodule,but
作者
胡晨波
钟智森
赖鹏华
HU Chenbo;ZHONG Zhisen;LAI Penghua(Department of General Surgery,Longnan First People's Hospital,Ganzhou,Jiangxi,341700,China)
出处
《当代医学》
2022年第34期14-17,共4页
Contemporary Medicine
