摘要
目的探究妊娠期糖尿病患者血清甲状腺激素水平和剖宫产术后感染风险之间的相关性。方法选取2019年9月至2020年12月于本院行剖宫产术的196例妊娠期糖尿病患者作为观察组,根据是否发生术后切口感染分为感染组(n=22)与未感染组(n=174),另选取同期因胎位不正于本院行剖宫产术的204例患者作为对照组。所有患者均检测糖化血红蛋白(HbAlc)、促甲状腺激素(TSH)、游离四碘甲状腺原氨酸(FT_(4))、游离三碘甲状腺原氨酸(FT_(3))、甲状腺素(T_(4))、三碘甲腺原氨酸(T_(3))水平,比较观察组与对照组术后切口感染发生率,比较感染组、未感染组和对照组HbAlc、TSH、FT_(4)、FT_(3)、T_(4)、T_(3)水平,采用Logistic回归分析妊娠期糖尿病患者剖宫产术后感染的危险因素。结果观察组术后切口感染发生率为11.22%,明显高于对照组的2.94%,差异有统计学意义(P<0.05)。3组FT_(4)、FT_(3)水平比较差异无统计学意义;3组HbAlc、TSH、T_(4)、T_(3)水平比较差异有统计学意义(P<0.05);感染组HbAlc、T_(4)、T_(3)水平均高于未感染组与对照组,TSH水平低于未感染组与对照组,且未感染组HbAlc、T_(4)水平均高于对照组,TSH水平低于对照组,差异有统计学意义(P<0.05)。Logistic回归分析显示,妊娠期糖尿病患者剖宫产术后感染的危险因素包括HbAlc、T_(4)、T_(3)水平(OR>1,P<0.05)。结论HbAlc、T_(4)、T_(3)水平与妊娠期糖尿病患者剖宫产术后感染密切相关,可作为诊断妊娠期糖尿病患者剖宫产术后后感染的诊断指标。
Objective To explore the correlation between serum thyroid hormone levels and the risk of infection after cesarean section in patients with gestational diabetes mellitus.Methods 196 patients with gestational diabetes mellitus who underwent cesarean section in our hospital from September 2019 to December 2020 were selected as the observation group,and they were divided into the infection group(n=22)and the non-infection group(n=174)according to whether they were infected or not after operasion,another 204 cases of cesarean section due to fetal malposition in our hospital during the same period were selected as the control group.The levels of glycosylated hemoglobin(HbAlc),thyroid stimulating hormone(TSH),free tetraiodothyronine(FT_(4)),free triiodothyronine(FT_(3)),thyroxine(T_(4))and triiodothyronine(T_(3))were measured in all patients,the incidence of postoperative incision infection was compared between the observation group and control group,and the levels of HbAlc,TSH,FT_(4),FT_(3),T_(4) and T_(3) were compared among the infection group,non-infection group and control group;Logistic regression was used to analyze the risk factors of postoperative infection in patients with gestational diabetes mellitus after cesarean section.Results The incidence of incision infection in the observation group was 11.22%,which was significantly higher than 2.94%in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in FT_(4) and FT_(3) levels among the three groups;there were significant differences in the levels of HbAlc,TSH,T_(4) and T_(3) among the three groups(P<0.05);the levels of HbAlc,T_(4) and T_(3) in the infected group were higher than those in the non-infection group and the control group,and the level of TSH was lower than that in the non-infection group and the control group,and the levels of HbAlc and T_(4) in the non-infection group were higher than those in the control group,and the level of TSH was lower than that in the control group,and the differenc
作者
蒋丽蓉
黄晓平
徐乙玉
JIANG Lirong;HUANG Xiaoping;XU Yiyu(Department of Obstetrics,Wuxi Yihe Maternity Hospital,Wuxi,Jiangsu,214000,China;Department of Obstetrics,Wuxi Maternity and Child Health Hospital,Wuxi,Jiangsu,214000,China;Department of Obstetrics,Dujiangyan Medical Center Obstetrics,Chengdu,Sichuan,611830,China)
出处
《当代医学》
2022年第36期56-59,共4页
Contemporary Medicine
关键词
妊娠期糖尿病
甲状腺激素
剖宫产
Gestational diabetes
Thyroid hormone
Cesarean section
