摘要
目的分析超高海拔地区(西藏拉萨)社区体检宫颈筛查人乳头瘤病毒(HPV)检测和细胞管薄层液基(TCT)检查结果。方法2020年7月至12月,我社区卫生服务中心对辖区所属7个居委会的妇女进行宫颈癌筛查。分析筛查结果,包括HPV感染的阳性率、TCT的检查结果、HPV感染的不同亚型与TCT阳性结果的关系,以及不同年龄段、不同初产年龄和不同绝经年龄的HPV感染率和TCT检查结果。结果筛查居民1185例,HPV感染160例,阳性率为13.5%,154例单一感染,6例双重感染。TCT筛查104例,阳性25例,阳性率为24.0%,包括不能明确意义的非典型鳞状细胞(ASCUS)9例、非典型鳞状细胞不除外高级别鳞状上皮内病变(ASC-H)3例和低度鳞状上皮内病变(LSIL)13例。我们将HPV亚型分类为HPV16型、18型和其他型。以40岁和60岁为界将HPV感染者分为3组,即<40岁组、40~60岁组和>60岁组。HPV其他型在3组中的感染率分别为75.6%、84.5%和100.0%,TCT筛查的阳性率分别为9.8%、17.5%和18.8%。按照初产年龄划分,160例HPV感染者中,包括<22岁43例、22~30岁94例、>30岁12例和未生育11例。比较绝经年龄>55岁组和未绝经组,HPV其他型在2组中的感染率分别为100.0%和82.7%,TCT检查的阳性率分别为42.9%和10.2%。结论HPV感染率和TCT阳性率分别为13.5%和24.0%,首次报告超高海拔地区社区体检宫颈筛查结果,有助于指导本地区宫颈癌的社区防治工作。
Objective To analyze the screening results of human papillomavirus(HPV)infection and thinprep cytology test(TCT)for cervical cancer in women residing at very high altitude(Lhasa,Tibet).Methods Our health service center undertook the task of cervical cancer screening for community residents in the period from July to December 2020,and the results were analyzed,including the positive rates of HPV infection and TCT,the association of HPV subtype with TCT,and the results of HPV and TCT among different age groups,different ages of first delivery,and different menopausal ages.Results 1185 residents were screened and 160(13.5%)were diagnosed with HPV infection,including 154 with single infection and 6 with double infection.104 residents were given the TCT test and 25(24.0%)had positive results,including 9 cases diagnosed with atypical squamous cells of undetermined significance(ASCUS),3 with atypical squamous cells cannot exclude hSIL(ASC-H)and 13 with low grade squamous intraepithelial lesions(LSIL).HPV subtypes were re-divided into 3 groups,including HPV 16,HPV 18 and HPV other type.For the association of HPV subtype and TCT with age,the positive rates of HPV other type and TCT test in people under 40 years,40~60 years and above 60 years were 75.6%,84.5%,100.0%and 9.8%,17.5%,18.8%,respectively.For the age of first delivery,43,94 and 12 people were under 22 years,22~30 years and above 30 years,and 11 people had not this experience.For the menopausal age,the positive rates of HPV other type and TCT in people who occurred after age 55 and un-menopausal women were 100.0%,82.7%and 42.9%,10.2%,respectively.Conclusion The positive rates of HPV infection and TCT test were 13.5%and 24.0%in our community residents.We reported the results at a very high altitude for the first time,which would be helpful for the prevention and control of cervical cancer in our community.
作者
普布仓决
泽仁卓玛
高春
王凯
闫丽娥
Pubucangjue;Zerenzhuoma;Gao Chun;Wang Kai;Yan Lie(Bakuo Community Health Service Center,Chengguan District,Lhasa,Tibet850000,China;不详)
出处
《山西医药杂志》
2023年第7期500-504,共5页
Shanxi Medical Journal
关键词
HPV感染
TCT
宫颈癌
社区防治
超高海拔
HPV Infection
TCT
Cervical Cancer
Community Prevention and Treatment
Very High Altitude
