摘要
目的探讨早期肺癌胸腔镜肺段切除及肺叶切除不同治疗方式的临床疗效。方法前瞻性选取2018年6月至2022年6月期间南京江北医院收治的70例术前分期Ⅰa期肺癌患者作为研究对象,按手术方式分为A组和B组。采取肺段切除+淋巴结采样的为A组(35例)、肺叶切除+淋巴结清扫的为B组(35例),分别比较两组患者手术时间、术中出血量、术后引流总量、引流管带管时间、并发症发生率、术后3个月肺功能、预后情况。结果A组手术时间高于B组,两组差异有统计学意义[(2.5±0.5)h vs(2.0±0.3)h,P<0.05],术中出血量两组差异无统计学意义[100.00(90.0,130.0)mL vs 110.00(95.0,135.0)mL,P>0.05]。术后引流量[(350.0±65.2)mL vs(450.0±78.5)mL]、引流管带管时间[(3.1±0.3)d vs(4.0±0.6)d]A组优于B组,差异有统计学意义。两组术后并发症发生率差异无统计学意义(P>0.05)。术后3个月肺功能,最大分钟通气量(MVV)、用力肺活量(FVC)和第1秒用力呼气容积(FEV_(1))比较A组明显优于B组,差异有统计学意义(P<0.05)术后定期随诊均未发现复发和远处血行转移。结论早期Ⅰa期肺癌胸腔镜肺段切除能减少术后引流量,减少引流管带管时间,更好的保护肺功能。
Objective To investigate the clinical efficacy of thoracoscopic segmental resection and lobectomy in the treatment of early lung cancer.Methods A total of 70 patients with lung cancer ofⅠa stage who received operation from June 2018 to 2022 at Nanjing Jiangbei Hospital were selected.The patients were divided into group A and group B according to the operation methods.Segmental resection and lymph node sampling were detected in group A,while otectomy and lymph node dissection were detected in group B.The surgical time,intraoperative bleeding,total postoperative drainage,drainage tube insertion time,incidence of complications,pulmonary function at 3 months after surgery,and prognosis were compared between the two groups.Results The surgical time in group A was higher than that in group B[(2.5±0.5)h vs(2.0±0.3)h,P<0.05],and there was no significant difference in intraoperative bleeding between the two groups[100.00(90.0,130.0)mL vs 110.00(95.0,135.0)mL,P>0.05].The postoperative drainage flow volume[(350.0±65.2)mL vs(450.0±78.5)mL,P<0.05]and drainage tube insertion time[(3.1±0.3)d vs(4.0±0.6)d,P<0.05]in group A were significantly better than those in group B.There was no significant difference in the incidence of postoperative complications(P>0.05).After 3 months of postoperative pulmonary function review,MVV,FVC,and FEV_(1) in group A were significantly better than those in group B,with statistical significance(P<0.05).Regular follow-up after surgery did not detect recurrence or distant hematogenous metastasis.Conclusion Thoracoscopic segmental resection of early-stageⅠa lung cancer can reduce postoperative drainage flow,reduce drainage tube insertion time,and better protect lung function.
作者
常江华
荣君
强光辉
CHANG Jianghua;RONG Jun;QIANG Guanghui(Department of Thoracic Surgery,Nanjing Jiangbei Hospital Affiliated to Nantong University,Nanjing,Jiangsu 210044,China)
出处
《中国临床研究》
CAS
2023年第6期856-859,共4页
Chinese Journal of Clinical Research
关键词
胸腔镜
早期肺癌
肺段切除
肺叶切除
肺功能
手术时间
引流
Thoracoscopy
Early lung cancer
Lung segment resection
Lobectomy
Pulmonary function
Surgical time
Drainage
