摘要
目的:探讨血清白蛋白(Alb)水平对颅脑损伤患者院内感染的影响。方法:回顾本院近四年收治颅脑损伤患者的临床资料,将其分为低Alb组59例(Alb<35 g/L)和Alb正常组88例(Alb≥35g/L),采用1:1倾向性评分匹配法均衡组间协变量,采用Cox比例风险回归模型分析院内感染的影响因素。结果:共匹配54对,两组各变量绝对标准化差异均<10%;匹配前后,低Alb组院内感染率均高于Alb正常组(P<0.05);匹配前后,低Alb均是院内感染的危险因素(P<0.05)。结论:血清Alb是颅脑损伤患者院内感染的影响因素。
Objective:To explore the effect of serum albumin(Alb)level on nosocomial infection in patients with craniocerebral injury.Method:The clinical data of patients with craniocerebral injury admitted to our hospital in the past four years were reviewed.They were divided into low Alb group of 59 cases(Alb<35 g/L)and normal Alb group of 88 cases(Alb≥35 g/L).The 1:1 propensity score matching method was used to balance the covariates between the groups,and the Cox proportional risk regression model was used to analyze the influencing factors of nosocomial infection.Results:A total of 54 pairs were matched,and the absolute standardization difference of each variable between the two groups was less than 10%.Before and after matching,the hospital infection rate of low Alb group was higher than that of normal Alb group(P<0.05).Before and after matching,low Alb was a risk factor for nosocomial infection(P<0.05).Conclusion:Serum Alb is the influencing factor of nosocomial infection in patients with craniocerebral injury.
作者
方毅琳
洪文明
Fang Yilin;Hong Wenming(Hefei Eighth People's Hospital;The First Affiliated Hospital of Anhui Medical University)
出处
《现代科学仪器》
2023年第3期78-82,共5页
Modern Scientific Instruments
基金
2019年安徽省自然科学基金,基金编号1908085QH379。
关键词
颅脑损伤
院内感染
血清白蛋白
倾向性评分匹配法
Craniocerebral injury
Nosocomial infection
Serum albumin
Propensity score matching method
