摘要
目的研究病情处于急性加重期的慢性阻塞性肺疾病患者采用吸入用布地奈德混悬液联合硫酸特布他林雾化液方案实施治疗的临床效果。方法选择2019年1月-2021年12月在本院进行治疗的80例病情处于急性加重期的慢性阻塞性肺疾病患者,根据所选治疗方案的不同将其分成对照组和治疗组。对照组中40例患者单纯采用吸入用布地奈德混悬液进行治疗;治疗组中40例患者采用吸入用布地奈德混悬液联合硫酸特布他林雾化液进行治疗。对比两组病情控制总有效率、治疗前后呼吸功能、肺部功能、炎症反应相关指标水平、呼吸功能复常、监测指标复常、治疗总时间、不良反应情况。结果治疗组患者病情控制总有效率高于对照组,组间数据比较差异有统计学意义(P<0.05);治疗组治疗前后呼吸功能、肺部功能、炎症反应相关指标水平的改善幅度大于对照组,组间数据比较差异有统计学意义(P<0.05);治疗组呼吸功能复常、监测指标复常、治疗总时间短于对照组,组间数据比较差异有统计学意义(P<0.05);治疗组不良反应少于对照组,组间数据比较差异有统计学意义(P<0.05)。结论病情处于急性加重期的慢性阻塞性肺疾病患者采用吸入用布地奈德混悬液联合硫酸特布他林雾化液方案实施治疗,能够迅速改善呼吸功能和肺部功能指标,有效控制炎症反应,减少不良反应,缩短治疗时间,使病情控制总有效率提高。
Objective To study clinical effect of inhaled budesonide suspension combined with terbutaline sulfate aerosol solution on chronic obstructive pulmonary disease patients at acute exacerbation stage.Methods The paper chose 80 patients with chronic obstructive pulmonary disease at acute exacerbation stage in our hospital from January 2019 to December 2021,and divided them into control group and treatment group based on different treatment options.40 cases in control group were treated with inhaled budesonide suspension only,40 cases in treatment group with inhaled budesonide suspension combined with terbutaline sulfate aerosol.Total effective rate of disease control,respiratory function,lung function,inflammatory response related indicators,respiratory function normalization,monitoring index normalization,total treatment time,and adverse reactions were compared before and after treatment between two groups.Results Total effective rate of disease control in treatment group was higher than control group,there was statistically significant difference in data comparison between the groups(P<0.05).Improvement in respiratory function,lung function,and inflammatory response related indicators before and after treatment in treatment group was greater than control group,data difference between the groups was statistically significant(P<0.05).Respiratory function and monitoring indicators normalized time and total treatment time of treatment group was shorter than control group,data difference comparison was statisticall y significant between the groups(P<0.05).Treatment group had fewer adverse reactions than control group,data difference comparison was statistically significant between the groups(P<0.05).Conclusion Combination of inhaled budesonide suspension and terbutaline sulfate aerosol can improve respiratory function and lung function indicators effectively,control inflammatory reaction,reduce adverse reactions,shorten treatment time,and improve overall effective rate of patients with chronic obstructive pulmonary dise
作者
王婧
WANG Jing(Yantai City Laishan District Laishan Street Community Health Service Center/Yantai City Laishan District The Second People's Hospital,Yantai,Shandong 264000)
出处
《智慧健康》
2023年第9期124-128,共5页
Smart Healthcare
关键词
急性加重期
慢性阻塞性肺疾病
吸入用布地奈德混悬液
硫酸特布他林雾化液
Acute exacerbation stage
Chronic obstructive pulmonary disease
Budesonide suspension for inhalation
Terbutaline sulfate aerosol
