摘要
目的了解汉中市2015—2021年流行性乙型脑炎(简称“乙脑”)流行病学特征,为本市乙脑预防控制提供依据。方法采用酶联免疫吸附试验(enzyme linked immunoadsordent assay,ELISA)检测汉中市2015—2021年乙脑疑似病例血清和脑脊液标本中的乙型脑炎病毒IgM抗体,并对检测结果进行分析。结果汉中市2015—2021年共检测乙脑疑似病例标本181例,阳性62例,占34.25%(62/181),集中于2017(22例)和2018年(19例)。7个监测年份乙脑阳性病例夏季(7至9月)多发,甘肃省陇南市输入型乙脑病例占比较大。确诊的62例乙脑阳性病例,男女性别比为1.30∶1。阳性率女性高于男性,差异无统计学意义(χ^(2)=2.04,P>0.01)。阳性病例10~<20岁年龄组最多(13例),40~<50岁组乙脑阳性率最高,占60.00%(12/20)。职业分布以农民和学生为主,占90.32%(56/62)。结论2015—2021年汉中市乙脑发病有季节性,防疫部门应密切关注流动人口发病风险,在乙脑流行高峰期做好重点人群保护工作。
Objectives To understand the epidemiological characteristics of epidemic encephalitis B in Hanzhong City from 2015 to 2021,and to provide evidence for the prevention and control of epidemic encephalitis B.Methods Enzyme linked immunosorbent assay(ELISA)was used to detect IgM antibodies to epidemic Encephalitis B virus in serum and cerebrospinal fluid samples of suspected cases of epidemic encephalitis B in Hanzhong City from 2015 to 2021 and the detection results were analyzed.Results A total of 181 suspected cases of epidemic encephalitis B were detected in Hanzhong City from 2015 to 2021,with 62 positive cases,accounting for 34.25%(62/181)concentrated in 2017(22 cases)and 2018(19 cases).The positive cases of epidemic encephalitis B mostly occurred in summer(July to September)in the seven monitoring years,and the imported cases accounted for a large proportion in Longnan City,Gansu Province.Among the 62 positive cases of epidemic encephalitis B diagnosed,the male to female gender ratio was 1.30:1.The positive rate was higher in females than in males,and the difference was not statistically significant(χ^(2)=2.04,P>0.01).Among the positive cases,the age group of 10 to<20 years old had the highest number of cases(13 cases),and the group of 40 to<50 years old had the highest positive rate of epidemic encephalitis B,accounting for 60.00%(12/20).The occupation distribution was dominated by farmers and students,accounting for 90.32%(56/62).Conclusion The incidence of epidemic encephalitis B shows seasonality in Hanzhong City from 2015 to 2021,and the epidemic prevention department should pay close attention to the incidence risk in the migrant population and do a good job of protecting key population during the peak epidemic period of epidemic encephalitis B.
作者
张久丁
韩亦非
邓彤
邹宁
陈真
张木林
刘红丽
ZHANG Jiuding;HAN Yifei;DENG Tong;ZOU Ning;CHEN Zhen;ZHANG Mulin;LIU Hongli(Hanzhong Center for Disease Control and Prevention,Shaanxi 723000,China)
出处
《医学动物防制》
2023年第6期573-575,579,共4页
Journal of Medical Pest Control
基金
国家科技重大专项课题(2018ZX10713002)。
关键词
乙脑
监测
防控
IGM抗体
汉中市
分析
Epidemic encephalitis B
Surveillance
Prevention and control
IgM antibody
Hanzhong City
Analysis
