摘要
关于小脑非运动功能的研究逐渐成为热点,包括工作记忆、语言、执行处理和奖赏等高级认知功能。小脑通过与大脑新皮层之间丰富的连接调控认知功能,小脑结构或功能异常可导致认知功能与社交行为受损,如自闭症谱系障碍(ASD)。本文就小脑的神经解剖基础、认知功能研究进展以及ASD患者小脑结构的变化等方面分别进行阐述,以期为进一步深入认识小脑的生理及病理生理作用提供参考。
The cerebellum is traditionally known for its crucial role in motor coordination,but current research suggests that it also plays a vital part in various cognitive functions,particularly those related to reward and motivation.In contrast,damage or dysfunction of the cerebellum has been linked to cognitive deficits and abnormal social behavior,including autism spectrum disorders(ASD).This article provides a comprehensive review of the neuronal features,neural projections,and involvement of the cerebellum in both cognitive processes and ASD.By examining this significant brain region,we hope to gain a better understanding of its physiological and pathophysiological effects on individuals.
作者
唐涣垚
周亮
Tang Huanyao;Zhou Liang(Key Laboratory of Brain Science Guizhou Institution of Higher Education,Zunyi Medical University,Zunyi Guizhou 563099,China)
出处
《遵义医科大学学报》
2023年第6期631-636,共6页
Journal of Zunyi Medical University
基金
国家自然科学基金资助项目(NO:82060224)
贵州省科技计划项目[NO:黔科合基础(2020)1Y088]
遵义市科技局遵义医科大学科学技术联合资金项目[NO:遵市科合HZ字(2021)194]。
关键词
小脑
神经环路
认知
奖赏
自闭症
cerebellum
neural circuits
cognition
rewarding
autism spectrum disorders
