摘要
目的:分析临床药师参与抗肿瘤药物分级管理的效果.方法:随机抽取2021年1月—4月在我院未进行临床药师参与抗肿瘤药物分级管理的长期使用抗肿瘤药物治疗的60例患者为干预前,2021年5月—9月实施临床药师参与抗肿瘤药物分级管理后为干预后.比较干预前后抗肿瘤药物使用的合理情况、不良反应发生率和治疗费用.结果:干预后患者使用抗肿瘤药物不合理率低于干预前,但差异无统计学意义(P>0.05);干预后不良反应总发生率为15.00%,低于干预前的50.00%,差异有统计学意义(P<0.05);干预后抗肿瘤药物费用高于干预前,但差异无统计学意义(P>0.05).干预后治疗费用、药品总费用低于干预前,但差异无统计学意义(P>0.05).结论:临床药师参与抗肿瘤药物分级管理能有效保证临床合理使用肿瘤药物,减少抗肿瘤药物不良反应的发生和避免患者医疗负担增加.
Objective:To analyze the effect of clinical pharmacists participating in the classification management of antitumor drugs.Methods:From January to April 2021,60 patients with long-term use of anti-tumor drugs who did not participate in the classification management of anti-tumor drugs by clinical pharmacists in our hospital were randomly selected as the pre-intervention group.From May to September 2021,clinical pharmacists participated in the classification management of anti-tumor drugs as the post-intervention group.The rational use of anti-tumor drugs,incidence of adverse reactions and treatment costs before and after intervention were compared.Results:The unreasonable rate of anti-tumor drugs after intervention was lower than that before intervention,but the difference was not statistically significant(P>0.05).The total incidence of adverse reactions after intervention was 15.00%,which was lower than 50.00%before intervention,and the difference was statistically significant(P<0.05).The cost of anti-tumor drugs after intervention was higher than that before intervention,but the difference was not statistically significant(P>0.05).The treatment cost and total drug cost after intervention were lower than those before intervention,but the difference was not statistically significant(P>0.05).Conclusion:The participation of clinical pharmacists in the classification management of antitumor drugs can effectively ensure the rational use of antitumor drugs in clinic,reduce the occurrence of adverse reactions of antitumor drugs and avoid the increase of medical burden of patients.
作者
徐杏华
关国娴
赖荣芬
杨伟杰
XU Xinghua;GUAN Guoxian;LAI Rongfen;YANG Weijie(Department of Pharmacy,Hui Ya Hospital of The First Affliated Hospital,Sun Yat-sen University,Huizhou 516081,Guangdong,China)
出处
《中国药物滥用防治杂志》
CAS
2023年第5期799-802,共4页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
2021年惠州市科技计划(医疗卫生)项目(编号:2021WC0106315)。
关键词
临床药师
抗肿瘤药物
分级管理
Clinical pharmacists
Antitumor drugs
Classification management
