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C-type lectin receptors as potential targets for the treatment of gastrointestinal diseases related to fungal infection

C型凝集素受体可作为真菌感染相关的胃肠道疾病的一个潜在治疗靶点
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摘要 Many microorganisms reside in the gastrointestinal tract and the dysbiosis of microorganisms can affect our health.Fungi have a relatively low level of presence(about 0.1%of the totalmicroorganisms)compared with bacteria,which makes it easier to underestimate their potential threat to health.However,fungal infections indeed participate in the onset and progression of many intestinal diseases,so they are crucially affecting our health[1,2].Recently,Li et al.described that C-type lectin receptors(CLRs)on myeloid cells,including Dectin-1,Dectin-2,Dectin-3,and Mincle,play an important role in the immune function induced by fungal pathogens of the intestinal microbiota[3].
出处 《Gastroenterology Report》 SCIE EI 2019年第5期376-377,I0003,共3页 胃肠病学报道(英文)
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