摘要
To the Editor,Portal hypertension(PH)is defined by a pathological increase in the pressure of the portal venous system,1 with liver cirrhosis as the most common cause.However,some other noncirrhotic diseases might cause PH;a condition referred to as noncirrhotic PH(NCPH).2 NCPH is a rare disease characterized by clinical signs of PH in the absence of cirrhosis,presenting with complications of PH including ascites,splenomegaly,esophagogastric varices,and variceal bleeding.3 Because of the similarities in clinical manifestations and imaging signs,NCPH is easily misdiagnosed as liver cirrhosis and thus raises difficulties in differential diagnosis.Although liver biopsy is still the gold standard for diagnosis,4 extensive workup including laboratory testing,hepatic imaging and liver biopsy is recommended for comprehensive NCPH diagnosis.
基金
supported by the National Natural Science Foundation of China(grant number 82103655).
