摘要
目的探讨肺原发黏膜相关淋巴组织(MALT)淋巴瘤的临床特征。方法收集2008年至2021年该院20例肺原发MALT淋巴瘤患者的临床、CT表现、病理、治疗信息,并行回顾性分析。结果20例患者男女比例相同;10例无明显呼吸系统临床表现;11例胸部CT表现为肺炎型改变;7例经肺穿刺确诊,6例纤维支气管镜(简称纤支管)未确诊后行肺穿刺确诊,4例纤支镜活检确诊,3例外科活检确诊;对CT表现与临床特征行相关性分析,显示肺部病灶的分布特征与年龄明显相关;病变偏侧性或分布位置与纵向分布倾向明显相关;影像类型与分布位置明显相关;8例未治疗,7例行化疗、1例行化疗+放疗,2例行手术切除+术后化疗,2例仅手术切除(其中1例复发)。结论肺原发MALT淋巴瘤发病率低,临床表现不典型,CT影像表现多为双侧类肺炎样改变,需临床足够重视,首选CT引导下肺穿刺检进行明确诊断。
Objective To analyze the clinical features of primary pulmonary mucosa associated lymphoid tissue(MALT)lymphoma.Methods The clinical manifestations,computed tomography(CT)features,histopathology and treatment information of 20 patients with primary pulmonary MALT diagnosed in this hospital from 2008 to 2021 were collected and analyzed retrospectively.Results The proportion of male and female was same in the 20 patients.A total of 10 cases had no obvious clinical features of respiratory system;11 cases showed pulmonary consolidation of pneumonia type on chest CT;seven cases were confirmed by CT-guided percutaneous lung biopsy;six cases were undetermined by bronchoscope but diagnosed by CT-guided percutaneous lung biopsy;four cases were diagnosed by bronchoscope biopsy,and three cases were confirmed by surgery.The correlation analysis between CT imaging and clinical features showed that the longitudinal distribution characteristics of pulmonary lesions were significantly correlated with age;The laterality or distribution position of the lesion was significantly correlated with the tendency of longitudinal distribution;The image type was also significantly correlated with the longitudinal distribution.A total of eight cases were untreated;seven cases were treated with chemotherapy;one case was treated with chemotherapy and radiotherapy;two cases were treated with postoperative chemotherapy;two cases were treated with only surgical resection,and one case recurred after separate surgical resection.Conclusion The incidence of primary pulmonary MALT lymphoma is low,and its clinical features are atypical.CT images are mostly bilateral pneumonia-like changes.CT images are mostly bilateral pneumonia-like changes,which needs much more clinical attention.
作者
皮强中
刘小华
梁岚
PI Qiangzhong;LIU Xiaohua;LIANG Lan(Department of respiratory and critical medicine,the First Affiliated Hospital of the Army Medical University,Chongqing 400038,China)
出处
《重庆医学》
CAS
2023年第11期1697-1701,共5页
Chongqing medicine
关键词
肺
原发性
黏膜相关淋巴组织
淋巴瘤
临床特征
回顾性研究
lung
primary
mucosa associated lymphoid tissue
lymphoma
clinical features
retrospective study
