摘要
目的:对比分析平阳霉素碘化油乳剂和聚乙烯醇子宫动脉栓塞方案治疗子宫肌瘤的疗效。方法:选取本院2018年5月至2020年5月收治的82例子宫肌瘤患者作为研究对象,基于子宫栓塞治疗方案中栓塞材料选取的不同将其分为两组。对照组42例选用平阳霉素碘化油乳剂作为栓塞材料,研究组40例选用聚乙烯醇作为栓塞材料。观察两组患者术前及术后6个月的超声影像学指标、血流动力指标和卵巢功能指标,统计治疗有效率、术后综合征发生率和复发率。结果:两组间治疗有效率比较差异无统计学意义(P>0.05)。治疗后两组患者的子宫体积和子宫肌瘤体积均较治疗前有显著降低(P<0.05),治疗后两组子宫体积和子宫肌瘤体积组间差异均无统计学意义(P>0.05)。治疗后两组患者的子宫肌瘤内部血供平均流速、收缩期峰值流速、最粗供血动脉管径和阻力指数均较治疗前有显著改善(P<0.05),治疗后两组各项血流动力指标组间差异均无统计学意义(P>0.05)。治疗后两组患者的促卵泡生长激素、雌二醇、血清孕酮和促黄体生成素指标与治疗前相比差异均无统计学意义(P>0.05),术前及术后6个月两组各项指标组间差异均无统计学意义(P>0.05)。研究组患者术后综合征发生率显著低于对照组(P<0.05),研究组患者复发率显著低于对照组(P<0.05)。结论:平阳霉素碘化油乳剂和聚乙烯醇子宫动脉栓塞方案均可以显著缩小子宫体积和子宫肌瘤体积,降低血供,均不会影响卵巢功能,聚乙烯醇子宫动脉栓塞方案术后综合征发生率和复发率更低。
Objective:To compare the efficacy of Pingyangmycin iodide oil emulsion and polyvinyl alcohol uterine arterial embolization in the treatment of uterine fibroids.Methods:82 patients with hysteromyoma from May 2018 to May 2020 were selected and divided into two groups on the basis of different embolic materials.42 patients in the control group were treated with Pingyangmycin iodide oil emulsion,and 40 patients in the study group were treated with polyvinyl alcohol emulsion.The indexes of ultrasonography,hemodynamics and ovarian function were observed before operation and 6 months after operation,and the effective rate of treatment,incidence of postoperative syndrome and recurrence rate were calculated.Results:There was no significant difference in the effective rate between the two groups(P>0.05).After treatment,the volume of uterus and Myoma of both groups were significantly lower than that before treatment(P<0.05).There was no significant difference between the two groups(P>0.05).After treatment,the mean flow velocity,peak systolic flow velocity,the diameter of the thickest artery and the resistance index of the two groups were significantly improved(P<0.05),there was no significant difference in hemodynamic parameters between the two groups after treatment(P>0.05).After treatment,there were no significant differences in serum levels of Fsh,Estradiol,progesterone and Lutropin Alfa between the two groups(P>0.05),there was no significant difference between the two groups before operation and 6 months after operation(P>0.05).The incidence of postoperative syndrome in the study group was significantly lower than that in the control group(P<0.05),and the recurrence rate in the study group was significantly lower than that in the control group(P<0.05).Conclusion:Both Pingyangmycin iodide oil emulsion and polyvinyl alcohol uterine arterial embolization can significantly reduce the size of uterus and uterine fibroids,reduce blood supply,and have no effect on ovarian function,the incidence of postoperative syndrome and rec
作者
甄卓
王玉良
Zhen Zhuo;Wang Yuliang(The First Department Outside the Hospital of the Tianjin Armed Police Corps,Tianjin,300000,China)
出处
《中外女性健康研究》
2023年第10期4-7,10,共5页
Women＇s Health Research
关键词
平阳霉素碘化油乳剂
聚乙烯醇
子宫动脉栓塞
子宫肌瘤
Pingyangmycin iodide oil emulsion
Polyvinyl alcohol
Uterine artery embolization
Uterine Leiomyoma
