摘要
目的探讨并分析早期先兆流产合并绒毛膜下血肿患者采用氨甲环酸联合地屈孕酮治疗的临床效果。方法选取87例早期先兆流产合并绒毛膜下血肿患者,根据随机数字表法将其分成对照组(n=44)与观察组(n=43)。对照组单纯采用地屈孕酮治疗,观察组在对照组的基础上采用氨甲环酸治疗。比较两组患者的临床治疗有效率、止血相关指标及治疗前后绒毛膜下血肿超声检测结果。结果治疗前,两组的绒毛膜下血肿及绒毛膜下血肿面积/孕囊面积比较,差异无统计学意义(P>0.05);治疗后,观察组患者的绒毛膜下血肿及绒毛膜下血肿面积/孕囊面积均明显低于对照组(P>0.05);观察组患者的止血控制时间、完全止血时间短于对照组(P<0.05);观察组患者的临床治疗总有效率高于对照组(P<0.05)。结论氨甲环酸联合地屈孕酮在早期先兆流产合并绒毛膜下血肿患者中的临床应用效果显著,能缩短出血时间,值得应用。
Objective To investigate and analyze the clinical efficacy of Tranexamic Acid combined with Didroxyprogesterone in the treatment of early threatened abortion with subchorionic hematoma.Methods A total of 87 patients with early threatened abortion combined with subchorionic hematoma were selected.The patients were divided into the control group(n=44)and the observation group(n=43)according to the random number table methods.The control group was treated with Didroxyprogesterone alone,and the observation group was treated with Tranexamic Acid on the basis of the control group.The clinical treatment efficiency,hemostasis related indexes and ultrasonic detection results of subchorionic hematoma before and after treatment were compared between the two groups.Results Before treatment,there was no significant difference in the area of subchorionic hematoma and subchorionic hematoma/gestational sac between the two groups(P>0.05).After treatment,the area of subchorionic hematoma and subchorionic hematoma/gestational sac in the observation group were significantly lower than those in the control group(P<0.05).The control time and complete hemostasis time of patients in the observation group were shorter than those in the control group(P<0.05).The total effective rate of the observation group was higher than that of the control group(P<0.05).Conclusion The clinical application effect of Tranexamic Acid combined with Didroxyprogesterone in the treatment of early threatened abortion with subchorionic hematoma is significant,which can shorten the bleeding time,and is worthy of application.
作者
孙艳
Sun Yan(Department of Obstetrics and Gynecology,People's Hospital of Lishui District in Nanjing City(Lishui Branch of the Affiliated Zhongda Hospital of Southeast University),Jiangsu Province,Nanjing 211200,China)
出处
《实用妇科内分泌电子杂志》
2023年第1期36-38,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
氨甲环酸
地屈孕酮
先兆流产
绒毛膜下血肿
出血时间
Tranexamic Acid
Didroxyprogesterone
Threatened abortion
Subchorionic hematoma
Bleeding time
