摘要
目的 探讨产前免疫学检验项目检测对孕产妇妊娠结局及新生儿结局的影响。方法 选择2020年7月—2022年6月在潍坊市益都中心医院产科接受产前检查的150例进行免疫学检验项目检测的孕产妇以及150例产前未进行免疫学检验项目检测的孕产妇作为研究对象,分别纳入研究组和对照组。对照组孕产妇仅进行常规产前检查,研究组孕产妇在常规检查的基础上进行免疫学检验,检验项目包括人类免疫缺陷病毒(HIV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒螺旋体(TP)以及TORCH检查。统计研究组孕产妇的HIV、HBV、HCV、TP阳性检出率以及TORCH检查结果,对结果异常的孕产妇进行干预。比较研究组与对照组的高危妊娠发生率、不良妊娠结局发生率、分娩方式、产后出血情况、新生儿Apgar评分以及患者满意度。结果 研究组孕产妇HIV、HBV、HCV、TP的阳性检出率分别为0.67%、4.00%、1.33%、2.00%;TORCH检查结果显示,弓形虫免疫球蛋白M(IgM)、IgG抗体的阳性检出率分别为2.67%、12.00%,风疹病毒IgG抗体的阳性检出率为33.33%,巨细胞病毒IgM、IgG抗体的阳性检出率分别为2.00%、89.33%。研究组高危妊娠和不良妊娠结局总发生率、剖宫产率均明显低于对照组(高危妊娠总发生率:3.33%比11.33%,妊娠不良结局总发生率:2.00%比8.67%,剖宫产率:3.33%比11.33%,均P<0.05),阴道自然分娩率明显高于对照组(72.00%比56.67%,P<0.05)。研究组的产后2 h和产后24 h出血量均明显少于对照组[产后2 h出血量(mL):194.71±42.69比282.65±63.18;产后24 h出血量(mL):485.62±65.09比590.87±84.16,均P<0.05],产后出血发生率明显低于对照组(2.67%比10.00%,P<0.05)。研究组新生儿娩出后1 min和5 min的Apgar评分均明显高于对照组[出生后1 min(分):8.76±0.45比8.37±0.34;出生后5 min(分):9.12±0.48比8.65±0.40,均P<0.05]。研究组孕妇对产前检查的总满意率明显高于对照组(98.00%比91.33
Objective To investigate the impact of prenatal immunological test on the outcomes of pregnant women and newborns.Methods From July 2020 to June 2022,150 pregnant women who received antenatal examination in obstetrics department of Weifang Yidu Central Hospital and 150 pregnant women who did not receive antenatal immunological examination were selected as study group and control group.The pregnant women in control group were only subject to routine antenatal examination.The pregnant women in study group were subject to immunological examination on the basis of routine antenatal examination.The test items included human immunodeficiency virus(HIV),hepatitis B virus(HBV),hepatitis C virus(HCV),treponema pallidum(TP)and TORCH test.The positive rates of HIV,HBV,HCV,TP and TORCH result of pregnant women in study group were counted,and the pregnant women with abnormal results were intervened.The high-risk pregnancy incidence,adverse pregnancy outcome,delivery mode,postpartum hemorrhage,Apgar score of newborns and satisfaction between two groups were compared.Results The positive rates of HIV,HBV,HCV and TP in study group were 0.67%,4.00%,1.33%and 2.00%.The TORCH test results showed that the positive rates of Toxoplasma gondii immunoglobulin M(IgM)and IgG antibodies were 2.67%and 12.00%,the positive rate of rubella virus IgG antibodies was 33.33%,and the positive rates of cytomegalovirus IgM and IgG antibodies were 2.00%and 89.33%.In study group,the total incidence of high-risk pregnancy and adverse pregnancy outcomes,and the cesarean section rate were lower than those in control group(total incidence of high-risk pregnancy:3.33%vs.11.33%,total incidence of adverse pregnancy outcomes:2.00%vs.8.67%,cesarean section rate:3.33%vs.11.33%,all P<0.05).The vaginal natural delivery rate was higher than that in control group(72.00%vs.56.67%,P<0.05).The bleeding volumes at 2 hours and 24 hours postpartum in study group were lower than those in control group[bleeding volume at 2 hours postpartum(mL):194.71±42.69 vs.282.65±63.18,
作者
孙洪芝
李明红
王振红
Sun Hongzhi;Li Minghong;Wang Zhenhong(Department of Clinical Laboratory,Weifang Yidu Central Hospital,Weifang 262500,Shandong,China)
出处
《实用检验医师杂志》
2023年第1期29-32,共4页
Chinese Journal of Clinical Pathologist
关键词
产科
孕产妇
产前检查
免疫学检验
Obstetrics department
Maternity
Prenatal examination
Immunological test
