摘要
目的探讨腹部CT检查+肠系膜上动脉(SMA)CT血管造影(CTA)联合凝血四项检测在缺血性结肠炎(IC)中的早期诊断价值。方法将2017年6月至2022年6月首都医科大学附属北京友谊医院及乌海市人民医院收治的80例疑似IC患者作为研究对象,均行腹部CT、SMA CTA、凝血四项[凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(Fib)、凝血酶原时间(TT)]检测和肠镜检查,以肠镜诊断结果为金标准,评价腹部CT+SMA CTA联合凝血四项检测对IC的诊断价值。结果80例患者中,肠镜检查诊断为IC者60例,非IC者20例。与非IC组相比,IC组PT缩短,APTT和TT延长,Fib降低(P<0.05);受试者工作特征(ROC)曲线显示,PT、APTT、Fib、TT诊断IC的最佳截断值分别为≤10.59s、>29.16s、≤3g/L和>18.41s。腹部CT+SMA CTA联合凝血四项检测诊断IC的AUC值为0.876,高于各项单一诊断(P<0.05)。结论腹部CT、SMA CTA和凝血四项检测对IC的早期诊断均有一定价值,但与各项单一诊断相比,腹部CT检查+SMA CTA联合凝血四项检测有助于提高IC的早期诊断效能。
Objective To investigate the early diagnostic value of abdominal CT and superior mesenteric artery(SMA)CT angiography(CTA)combined with four coagulation tests in ischemic colitis(IC).Methods A total of 80 patients who were suspected of IC and admitted to Beijing Friendship Hospital,Capital Medical University and Wuhai People’s Hospital from June 2017 to June 2022 were selected as the research subjects.Abdominal CT,SMA CTA,detection of four coagulation indicators[prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(Fib)and prothrombin time(TT)],and intestinal endoscopy were performed.The diagnosis results of intestinal endoscopy were taken as the golden standard to evaluate the diagnostic value of abdominal CT and SMA CTA combined with four coagulation tests in IC.Results In this research,intestinal endoscopy diagnosed 60 patients with IC and 20 patients without.PT was shorter,APTT and TT were longer,and Fib level was lower in the IC group than in the non-IC group(P<0.05).The receiver operating characteristic(ROC)curve showed that the best cut-off values of PT,APTT,Fib and TT to diagnose IC were≤10.59s,>29.16s,≤3g/L and>18.41s,respectively.The AUC of abdominal CT and SMA CTA combined with four coagulation tests to diagnose IC was 0.876,larger than that of single diagnosis(P<0.05).Conclusion Abdominal CT,SMA CTA and four coagulation tests are all helpful for early diagnosis of IC.Compared with single diagnosis,abdominal CT and SMA CTA combined with four coagulation tests can improve the early diagnosis of IC.
作者
信亮亮
温智
XIN Liang-Liang;WEN Zhi(Digestive Department of Beijing Friendship Hospital Affiliated to Capital Medical University,Beijing 100050,China;Department of Gastroenterology,Wuhai People's Hospital,Inner Mongolia 016000,China)
出处
《中国CT和MRI杂志》
2023年第6期139-140,152,共3页
Chinese Journal of CT and MRI
