摘要
目的研究容积弧形调强放射治疗(VMAT)计划机器跳数与计划验证通过率的相关性。方法回顾性选取2020年1—10月在柳州市工人医院放疗的20例鼻咽癌和30例宫颈癌患者的VMAT计划,采用德国PTW公司的Detector 1500矩阵和OCTAVIUS 4D验证模体进行剂量测量,分析3%/2 mm、2%/2 mm条件下相关计划的剂量验证通过率。采用Pearson法双变量相关性分析对VMAT计划的机器跳数MU与计划验证通过率的相关性进行分析。结果3%/2 mm标准下鼻咽癌单弧、双弧、单双弧汇总计划机器跳数与γ通过率的相关系数分别为-0.873(P<0.001)、-0.800(P<0.001)、-0.781(P<0.001),宫颈癌计划为-0.493(P=0.006)。2%/2 mm标准下鼻咽癌单弧、双弧、单双弧汇总计划机器跳数与γ通过率的相关系数分别为-0.842(P<0.001)、-0.770(P<0.001)、-0.748(P<0.001),宫颈癌计划为-0.531(P=0.003)。结论VMAT计划的机器跳数与计划验证通过率成极显著的负相关关系。
Objective To analyze the correlation between the monitor units and pass rate of plan dose verification in the volumetric intensity modulated arc therapy(VMAT)plan.Methods VMAT plans for 20 patients with nasopharyngeal carcinoma(NPC)and 30 patients with cervical cancer who underwent radiotherapy at Liuzhou Workers'Hospital from January to October 2020 were retrospectively chosen.The Detector 1500 array and Octavius 4D phantom from German PTW company were used for dose measurement.The pass rates of dose verification of relevant plans were analyzed under the conditions of 3%/2 mm and 2%/2 mm.The correlation between the monitor units and pass rate of plan dose verification in VMAT plans was assessed by Pearson's bivariate correlation analysis.Results Under the condition of 3%/2 mm,the correlation coefficients between the monitor units and gamma pass rate were-0.873(P<0.001),-0.800(P<0.001),-0.781(P<0.001),-0.493(P=0.006)for NPC_1Arc,NPC_2Arc,NPC_1Arc+NPC_2Arc and Cervix_2Arc,respectively.Under the condition of 2%/2 mm,the correlation coefficients between the monitor units and gamma pass rate were-0.842(P<0.001),-0.770(P<0.001),-0.748(P<0.001)and-0.531(P=0.003)for NPC_1Arc,NPC_2Arc,NPC_1Arc+NPC_2Arc and Cervix_2Arc,respectively.Conclusion Significant negative correlation can be observed between the monitor units and plan dose verification pass rate in VMAT plan.
作者
谭军文
龙雨松
贺先桃
李钢
冯永富
王占宇
Tan Junwen;Long Yusong;He Xiantao;Li Gang;Feng Yongfu;Wang Zhanyu(Department of oncology,Liuzhou Worker's Hospital,Liuzhou 545005,China)
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2023年第6期546-550,共5页
Chinese Journal of Radiation Oncology
基金
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20200966)
广西重点研发计划(桂科AB22035026)
柳州市科技计划项目(2022SB011)。
关键词
容积弧形调强放射治疗
计划验证
机器跳数
相关性
鼻咽肿瘤
宫颈肿瘤
Volumetric intensity modulated arc therapy
Plan dose verification
Monitor units
Correlation
Nasopharyngeal carcinoma
Uterine cervical neoplasms
