摘要
目的探讨早产新生儿肺炎患儿红细胞输注量影响因素及其对喂养不耐受的预测价值。方法收集272例输注红细胞治疗的早产新生儿肺炎患儿作为研究对象,调查红细胞输注量,采用多元线性回归分析早产新生儿肺炎患儿红细胞输注量的影响因素。采用受试者工作曲线(ROC)分析红细胞输注量对早产新生儿肺炎患儿喂养不耐受的预测价值。结果早产新生儿肺炎患儿红细胞输注量均值为(76.19±26.03)mL。多元线性回归分析显示,胎龄、出生体重、采血量和输血前血红蛋白水平是早产新生儿肺炎患儿红细胞输注量的影响因素(B=-1.930、-6.215、1.041、-0.249,P<0.05)。早产新生儿肺炎患儿喂养不耐受发生率为19.5%。喂养不耐受组患儿红细胞输注量多于非喂养不耐受组(P<0.05)。ROC分析显示,红细胞输注量预测喂养不耐受的曲线下面积(AUC)为0.755。结论胎龄、出生体重、采血量和输血前血红蛋白水平是早产新生儿肺炎患儿红细胞输注量的影响因素。早产新生儿肺炎患儿喂养不耐受发生率高,红细胞输注量对喂养不耐受的发生具有较好的预测价值,临床上尽量减少医源性失血,减少输血量。
Objective To investigate the influencing factors of red blood cell transfusion volume for premature neonatal pneumonia and its predictive value for feeding intolerance.Methods 272 infants of premature neonatal pneumonia treated with red blood cell transfusion were collected as the research objects.Red blood cell transfusion volume was investigated and its influencing factors were analyzed by multiple linear regression.Receiver operating curve(ROC)was used to analyze the predictive value of red blood cell transfusion volume on feeding intolerance in infants with premature neonatal pneumonia.Results The average red blood cell transfusion volume in infants with premature neonatal pneumonia was(76.19±26.03)mL.Multiple linear regression analysis showed that gestational age,birth weight,volume of blood collection and hemoglobin level before blood transfusion were influencing factors of red blood cell transfusion volume in infants with premature neonatal pneumonia(B=-1.930,-6.215,1.041,-0.249,P<0.05).The incidence of feeding intolerance in infants with premature neonatal pneumonia was 19.5%.The transfusion volume of feeding intolerance group was significantly higher than that of the nonfeeding intolerance group(P<0.05).ROC analysis showed that the area under curve(AUC)of red blood cell transfusion volume for predicting feeding intolerance was 0.755.Conclusion Gestational age,birth weight,volume of blood collection and hemoglobin level before blood transfusion are influencing factors of red blood cell transfusion volume in infants with premature neonatal pneumonia.The incidence of feeding intolerance in premature neonatal pneumonia is high.The red blood cell infusion volume is of good predictive value for the occurrence of feeding intolerance.Latrogenic blood loss and red blood cell transfusion volume should be minimized clinically.
作者
王丽莉
王建荣
WANG Lili;WANG Jianrong(Department of Blood Transfusion,The Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830001,China;Department of Neonatal Pediatrics,The Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830001,China)
出处
《中国输血杂志》
CAS
2023年第5期377-380,共4页
Chinese Journal of Blood Transfusion
关键词
早产
新生儿肺炎
输血
影响因素
喂养不耐受
premature
neonatal pneumonia
transfusion
influencing factors
feeding intolerance
