摘要
目的探究单次激发快速自旋回波(SSFSE)序列在阻塞性睡眠呼吸暂停综合征(OSA)上气道动态成像的可行性,并比较SSFSE序列和小角度扰相梯度回波(FSPGR)序列在上气道动态成像的优缺点。方法前瞻性搜集2021年8月至12月华中科技大学协和深圳医院确诊的OSA患者22例(女性8例)。所有患者均完成上气道MRI检查,包括SSFSE序列和FSPGR序列单层连续动态扫描。分别对两种动态成像数据进行主观评价和客观评价,主观评价指标包括:图像伪影及变形程度、气管运动流畅性、气管边缘清晰程度和气管周围肌肉、脂肪等软组织层次分辨率,由两位医师对上述指标进行分级(1~3级)。客观测量包括:图像信噪比(SNR)、对比噪声比(CNR)、上气道面积和上气道径线。采用Fisher精确检验评价主观指标,采用配对t检验或秩和检验比较两种序列的SNR和CNR。采用一致性检验(ICC)比较两种序列在上气道面积和上气道径线测量中的一致性。结果主观评价:SSFSE序列和FSPGR序列在图像伪影及变形程度、气管运动流畅性、气管边缘清晰程度方面差异无统计学意义(P>0.05)。SSFSE序列对气管周围肌肉、脂肪等软组织层次分辨率优于FSPGR序列,差异具有统计学意义(P<0.05)。客观评价:FSPGR序列和SSFSE序列在图像测得的上气道面积和上气道径线结果均无明显差别(所得ICC值均为0.912~0.977,P<0.05),观察者间测量结果一致性较好。FSPGR序列在软腭、舌根和会厌组织的SNR及CNR均较SSFSE序列高,差异有统计学意义(P<0.05)。结论上气道MR动态成像中,SSFSE序列和FSPGR序列在气管测量上具有较高一致性,均可用于上气道阻塞程度的评估。SSFSE序列在软组织层次分辨率优于FSPGR序列,而FSPGR序列在SNR和CNR方面优于SSFSE序列。
Objective To investigate the feasibility of SSFSE sequence in upper airway dynamic MR imaging in patients with obstructive sleep apnea,and to compare SSFSE sequence with FSPGR sequence in upper airway dynamic MR imaging.Methods A total of 22 patients with OSA were recruited in Huazhong University of Science and Technology Union Shenz⁃hen Hospital from August 2021 to December 2021.Single⁃slice continuous dynamic MR scanning of upper airway were per⁃formed on all patients including SSFSE sequence and FSPGR sequence.We evaluated the two dynamic imaging sequences using both subjective indices and objective indices.Subjective indices include image artifact,degree of deformation,airway movement fluency,and airway edge clarity,which were graded by two physicians(grade 1-3).Objective measurements include image signal⁃to⁃noise ratio(SNR),contrast⁃to⁃noise ratio(CNR)and airway diameter.Fisher exact test was used for the subjective indices evaluation,and paired t test or wilcoxon test was used to compare the SNR and CNR of the two se⁃quences.The ICC test was used to compare the consistency of both sequences in the measurements of the airway areas and sagittal diameters.Results Subjective evaluations showed that there was no significant difference in the image artifact,degree of deformation and airway edge clarity between the SSFSE sequence and the FSPGR sequence(P>0.05).The SS⁃FSE sequence had better resolution for surrounding muscles and fat than the FSPGR sequence(P<0.05).Objective evaluation indicated that there was no significant difference in the upper airway area and sagittal diameter measurements between the two sequences(ICC were between 0.912-0.977,P<0.05),and the consistency of measurement results among ob⁃servers was good.The SNR and CNR of FSPGR sequence in soft palate,root of tongue and epiglottis were higher than those of SSFSE sequence and the difference was statistically significant(P<0.05).Conclusion SSFSE sequence and FSPGR sequence have high consistency in upper airway measurement.Thus
作者
魏发建
林仕伟
林晓珊
陈胜利
邱迎伟
WEI Fajian;LIN Shiwei;LIN Xiaoshan(Department of Radiology,Huazhong University of Science and Technology Union Shenzhen HospitalShenzhen,Guangdong Province 518000,P.R.China)
出处
《临床放射学杂志》
北大核心
2023年第4期597-602,共6页
Journal of Clinical Radiology
