摘要
目的观察前部缺血性视神经病变(anterior ischemic optic neuropathy,AION)的多模式影像学数据特征,以期提高临床AION诊断的准确性。方法回顾性分析2020年1月—2022年1月在江苏省中医院52例确诊为前部缺血性视神经病变患者的临床病例资料。患者行全身一般情况的检查和眼底影像学检查。包括眼底彩色照相、30°视野、频域光学相干断层扫描(spectral-domain optical coherence tomography,SD-OCT)及荧光素眼底血管造影(fundus fluorescein angiography,FFA)检查。分析AION患者眼底影像学特征。结果纳入本研究患者52例(52只眼)。眼底彩色照相以视盘肿胀为主,伴或不伴线片状出血(36只眼,69.2%)。30°视野检查以下方视野缺损为主(23只眼,49.0%)。FFA检查在早期以上方全部或部分视盘呈低荧光为主(23只眼,48.9%),晚期以视盘荧光素渗漏为主(32眼,68.1%)。SD-OCT检查中,与对照组比较,观察组视盘面积、盘沿面积、视盘周围神经纤维(pRNFL)厚度、T(颞侧)、S(上方)、N(鼻侧)及I(下方)pRNFL厚度均升高,差异有统计学意义(P<0.001),平均C/D比率及视杯体积均降低,差异有统计学意义(P<0.001),表明观察组视盘较对照组更为拥挤。结论通过分析AION患者眼底彩色照相、30°视野、FFA及SD-OCT检查的影像学特征,可以互相补充、全面评估患者病情。
Objective To observe the characteristics of multimodality imaging data of anterior ischemic optic neuropathy(AION)with the aim of improving the accuracy of clinical anterior ischemic optic neuropathy(AION)diagnosis.Methods Retrospective analysis of clinical case data of patients diagnosed with anterior ischemic optic neuropathy in Jiangsu Provincial Hospital of Traditional Chinese Medicine from January 2020 to January 2022.Fifty-two patients underwent general examination of the whole body and fundus imaging.The fundus color photography,30°field of view,spectral-domain optical coherence tomography(SD-OCT)and fundus fluorescein angiography(FFA)were included.The fundus imaging features of AION patients were analyzed.Results Fifty-two patients(52 eyes)were included in this study.Fundus color photography was dominated by optic disc swelling with or without linear hemorrhage(36 eyes,69.2%).30°visual field examination was dominated by inferior visual field defects(23 eyes,49.0%).FFA examination was predominantly hypofluorescent in all or part of the superior optic disc in the early stage(23 eyes,48.9.0%),and fluorescein leakage from the optic disc was predominant in the late stage(32 eyes,68.1%).In SD-OCT,compared with the control group,the optic disc area,disc rim area,peripapillary optic disc nerve fiber(pRNFL)thickness,T(temporal),S(superior),N(nasal),and I(inferior)pRNFL thickness were all increased in the observation group,the difference was statistically significant(P<0.001),and the mean C/D ratio and optic cup volume were lower,the difference was statistically significant(P<0.001),indicating that the optic disc was more crowded in the observation group than in the control group.Conclusion can complement each other and comprehensively evaluate the patient´s condition analyzing the imaging features of fundus color photography,30°visual field,FFA and SD-OCT examinations in patients with AION.
作者
王春秀
夏颖
魏伟
WANG Chunxiu;XIA Ying;WEI Wei(Department of Ophthalmology,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine(Jiangsu Provincial Hospital of Traditional Chinese Medicine),Nanjing,Jiangsu Province,210029 China)
出处
《世界复合医学》
2023年第2期10-13,18,共5页
World Journal of Complex Medicine
关键词
回顾性研究
前部缺血性视神经病变
多模式数据特征
Retrospective study
Anterior ischemic optic neuropathy
Multimodal data characteristics
