摘要
目的:对密切接触者主动筛查策略进行成本-效用分析,为肺结核的早期发现与防治策略提供科学依据。方法:建立密切接触者筛查策略的决策树-Markov模型,比较病例被动筛查策略与病例主动筛查策略的成本-效用。结果:与病例被动筛查策略相比,采用终身一次的病例主动筛查策略、终身两次不连续的病例主动筛查策略、每年一次的病例主动筛查策略的潜伏感染发生率、结核病发病率、死亡率均依次降低,并且每增加1 QALY的花费分别为8 973.3元、8 995.0元、10 801.2元,均低于WTP阈值标准,3种病例主动筛查策略均具有成本-效用优势。结论:对密切接触者连续开展主动筛查具有较高的成本-效用价值,是一项经济有效的公共卫生干预措施。
Objective:To analyze the cost-effectiveness of the active screening strategy for close contacts,and provide scientific basis for the early detection and prevention of tuberculosis.Methods:The decision tree Markov model of close contact screening strategy was established to compare the cost-effectiveness of passive screening strategy and active screening strategy.Results:Compared with the passive screening strategy,the incidence of latent infection,incidence rate of tuberculosis,and mortality of the active screening strategy once a year,the discontinuous active screening strategy twice a lifetime and the active screening strategy once a year all decreased in turn.The cost of each additional 1QALY was 8973.3 yuan8995 yuan,and 10801.2 yuan,lower than the WTP threshold standard.These three active screening strategies all had cost utility advantages.Conclusion:As an economic and effective public health intervention measure,continuous active screening for close contacts has high cost-effectiveness value.
作者
包亮亮
加依娜·拉兹别克
张燕
胥婉婷
毛宏凯
玛依沙·达肯
夏文俊
曹明芹
BAO Liang-liang;Jiayina Lazibieke;ZHANG Yan;XU Wan-ting;MAO Hong-kai;MA YISHA Da-ken;XIA Wen-jun;CAO Mng-Qin(School of Public Health,Xinjiang Medical University,Urumqi 830011,China)
出处
《中国卫生经济》
北大核心
2023年第4期65-69,共5页
Chinese Health Economics
基金
国家自然科学基金项目(82060622,U1903123)。
关键词
肺结核
密切接触者
病例主动筛查
病例被动筛查
成本-效用分析
pulmonary tuberculosis
close contacts
active case finding
passive case finding
cost-effectiveness analysis
