摘要
目的 探讨子宫内膜异位症患者中医体质类型分布情况及相关影响因素。方法 遵循临床流行病学调查方法,选取2020年10月—2022年3月就诊于首都医科大学附属北京妇产医院和中国中医科学院广安门医院的600例子宫内膜异位症患者,收集患者临床资料,并进行体质判定,分析子宫内膜异位症的中医体质分布情况及相关的影响因素。结果 600例患者中偏颇体质占69%,各偏颇体质分布:兼夹质>血瘀质>阳虚质>气郁质>痰湿质>湿热质>气虚质>阴虚质>特禀质。合并痛经者,体质以兼夹质、平和质、阳虚质为主;合并慢性盆腔痛、不孕、月经异常者,体质均以兼夹质、平和质、血瘀质为主;无症状患者,体质以平和质、兼夹质、血瘀质为主。r-AFS分期Ⅲ~Ⅳ期患者偏颇体质比例显著高于Ⅰ~Ⅱ期患者(P<0.05);偏颇体质中,Ⅰ~Ⅱ期以兼夹质、痰湿质、血瘀质为主,Ⅲ~Ⅳ期以兼夹质、血瘀质、阳虚质、气郁质为主,且兼夹质和血瘀质比例显著高于Ⅰ~Ⅱ期,差异均有统计学意义(P均<0.05)。血清CA125≥35 IU/mL的患者偏颇体质比例和Ⅲ~Ⅳ期患者比例均高于血清CA125<35 IU/mL的患者,差异均有统计学意义(P均<0.05);病程<3年、病程3~5年、病程6~10年、病程>10年的患者偏颇体质比例及分布存在显著差异(P<0.05),且随着病程的延长,偏颇体质比例呈逐渐升高趋势;年龄≤35岁和年龄>35岁的患者体质分布差异无统计学意义(P>0.05);偏颇体质人群中焦虑抑郁/烦躁抑郁患者比例显著高于平和质人群,差异有统计学意义(P<0.05)。结论 子宫内膜异位症患者偏颇体质比例较高,不同的临床表现有不同的体质分布,且患者体质分布与疾病的严重程度、病程以及性情密切相关。
Objective It is to explore the distribution of TCM constitution types and related influencing factors in patients with endometriosis.Methods This study followed the clinical epidemiological investigation method,600 patients with endometriosis treated in Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University and Guang’anmen Hospital of the China Academy of Chinese Medical Sciences from October 2020 to March 2022 were selected.Their clinical data was collected,and their physique was diagnosed to analyze the distribution of TCM physique of endometriosis and related influencing factors.Results 69%of the 600 patients with endometriosis had a biased constitution.The distribution of each biased constitution was as follows:accompanied constitution>blood stasis constitution>yang deficiency constitution>qi stagnation constitution>phlegm damp constitution>damp-heat constitution>qi deficiency constitution>yin deficiency constitution>special constitution.In the patients with endometriosis combined with dysmenorrhea,the constitution were mainly accompanied constitution,normal constitution,and yang-deficiency constitution;In the patients with chronic pelvic pain,infertility,and abnormal menstruation,the constitution were accompanied constitution,normal constitution,and blood stasis constitution;In the asymptomatic patients with endometriosis,the constitution were mainly accompanied constitution,normal constitution,and blood stasis constitution.The proportion of biased constitution in patients with endometriosis at r-AFSⅢ-Ⅳstage was significantly higher than that in patients with endometriosis atⅠ-Ⅱstage(P<0.05).Among the patients with biased constitutions,the patients at stageⅠ-Ⅱwere mainly with accompanied constitution,phlegm-damp constitution,and blood stasis constitution,while those at stageⅢ-Ⅳwere mainly with,blood stasis constitution,yang deficiency constitution,and qi stagnation constitution,and also the proportions of accompanied constitution and blood stasis constitution we
作者
韩倩
王子衿
石举梅
赵瑞华
武颖
HAN Qian;WANG Zijin;SHI Jumei;ZHAO Ruihua;WU Ying(Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University/Beijing Maternal and Child Health Care Hospital,Beijing 100026,China;Guang’anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China)
出处
《现代中西医结合杂志》
CAS
2023年第7期920-925,共6页
Modern Journal of Integrated Traditional Chinese and Western Medicine
基金
北京市中医药科技发展资金项目(QN-2020-27)。
关键词
子宫内膜异位症
中医体质
偏颇体质
影响因素
endometriosis
TCM constitution
biased constitution
influencing factors
