摘要
目的:优化复方党参的水煎提取工艺。方法:以加水量、浸泡时间、煎煮时间、煎煮次数为考察因素,以毛蕊异黄酮葡萄糖苷、甘草苷、阿魏酸、党参炔苷的层次分析法(AHP)-熵权法综合评分为考察指标,结合响应面法优化复方党参的水煎提取工艺。结果:实验得到复方党参的最佳提取工艺为加水12倍,浸泡90min,煎煮40min,煎煮2次。结论:本研究优化了复方党参的水煎提取工艺,为后续药效和作用机制研究提供基础。
Objective:To optimize the decoction extraction process of compound Codonopsis pilosula.Methods:The water content,soaking time,decocting time and decocting times were taken as the factors,and the AHP-entropy weight method was used as the evaluation index to optimize the decocting extraction process of compound Codonopsis pilosula.Results:The best extraction process of compound Codonopsis pilosula was 12 times of water,90 minutes of immersion,40 minutes of decoction,and twice of decoction.Conclusion:This study optimized the decoction extraction process of compound Codonopsis pilosula,and provided a basis for the follow-up study of drug efficacy and mechanism of action.
作者
杨杰
魏文一
景彩芳
李钦青
Yang Jie;Wei Wenyi;Jing Caifang;Li Qinqing(National International Joint Research Center for Molecular Chinese Medicine,Shanxi University of Chinese Medicine,Shanxi,030024;Shanxi Key Laboratory of Chinese Medicine Encephalopathy,Shanxi University of Chinese Medicine,Shanxi,030024)
出处
《当代化工研究》
CAS
2023年第10期166-168,共3页
Modern Chemical Research
基金
山西省重点研发计划(国际科技合作)重大区域创新合作项目“基于新型药物靶点CKLF1的党参抗脑缺血活性物质发现技术”(项目编号:201803D421006)
山西中医药大学研究生创新创业项目“一种提高免疫力的复方党参固体饮料的制备”(项目编号:2021CX046)
山西中医药大学科技创新能力培育项目“潞党参补益物质的绿色制造与分子药理学研究”(项目编号:2021PYQN-10)。
关键词
复方党参
AHP-熵权法
响应面
compound codonopsis pilosula
AHP-Entropy method
response surface
