摘要
高血压是21世纪对人类健康最具威胁性的慢性疾病之一,是全世界死亡归因的最主要危险因素,血压升高可显著增加冠状动脉粥样硬化性心脏病、心力衰竭、终末期肾病以及认知减退等并发症的发生率,被称为“无声杀手”。目前对于患者血压的监测仍以外周动脉压为主,治疗方案的选择同样以外周动脉压为依据。随着ASCOT-CAFé等试验结果的问世,大众开始重视中心动脉压的临床地位。因此,基于高血压在全球及中国的现状,综述原发性高血压患者中心动脉压对心、脑、肾等靶器官损害的影响,并简述不同抗高血压药对中心动脉压的治疗效果以及目前尚存的一些问题。
Hypertension is one of the most threatening chronic diseases to human health in the 21st century and is the main risk factor for attribution of death all over the world.High blood pressure can significantly increase coronary heart disease,heart failure,end-stage renal disease,cognitive decline and other complications,known as the“silent killer”.At present,peripheral arterial pressure is the main monitoring method for patients’blood pressure,and the choice of treatment plan is also based on peripheral arterial pressure.However,with the advent of ASCOT-CAFéand other trial results,the public began to pay attention to the clinical status of central arterial pressure.Therefore,based on the current situation of hypertension in the world and China,this paper describes in detail the effects of central arterial pressure in primary hypertension patients on the damage of heart,brain and kidney target organs,and briefly describes the therapeutic effects of different antihypertensive drugs on central arterial pressure and some existing problems.
作者
孙玉
郭守玉
龙明智
SUN Yu;GUO Shouyu;LONG Mingzhi(The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210000,Jiangsu,China;Department of Cardiology,The Second Affiliated Hospital of Nanjing Medical University,Nanjing 210000,Jiangsu,China)
出处
《心血管病学进展》
CAS
2023年第5期457-459,464,共4页
Advances in Cardiovascular Diseases
关键词
中心动脉压
靶器官损害
外周动脉压
Central arterial pressure
Target organ damage
Peripheral arterial pressure
