摘要
目的探索乳腺癌患者双靶治疗期间的症状群及对生活质量的影响,为乳腺癌症状高效管理提供依据。方法采用横断面研究方法,选取一般资料问卷、中文版记忆症状评估量表、中文版乳腺癌患者生活质量测定量表,对185例HER-2阳性乳腺癌女性患者进行问卷调查。结果通过主成分分析提取4类症状群,分别命名为皮肤黏膜症状群、胃肠道症状群、情绪症状群和神经症状群。乳腺癌患者生活质量平均得分为(100.01±14.76)分,症状群与患者的生活质量呈负相关。多元线性回归分析结果显示,生活质量受年龄、家庭月收入、婚姻状况、病理分期、激素受体状态和症状群等因素的影响(均P<0.05)。结论乳腺癌患者在双靶治疗期间存在着多种症状群,症状群负性影响生活质量,且影响因素较多,医护人员应针对症状群与影响因素制订管理策略,以提高管理效果。
Objective To explore the symptom group and quality of life of breast cancer patients during dual-target therapy,and to provide guidance for effective symptom management of breast cancer.Methods Using cross-sectional research methods,185 female patients with HER-2 positive breast cancer were investigated with General information questionnaire,the Chinese version of the Memory Symptom Assessment Scale and the Chinese version of the breast cancer patients′quality of life scale.Results Four symptom groups were extracted by principal component analysis,which were named as skin and mucosa symptom group,gastrointestinal symptom group,emotional symptom group and neurological symptom group.The average score of quality of life of breast cancer patients was(100.01±14.76),and the symptom group was negatively correlated with the quality of life of patients.Multiple linear regression analysis showed that the quality of life was affected by age,family monthly income,economicstatus,maritalstatus,pathological stage,hormone receptor status and symptom group(all P<0.05).Conclusion Breast cancer patients have a variety of symptom cluster during dual-target therapy,which negatively affect the quality of life.Medical staffs should formulate management strategies to improve the effect according to the symptom cluster and related factors.
作者
李盼盼
李红梅
张俊
李苗
杨佳
Li Panpan;Li Hongmei;Zhang Jun;Li Miao;Yang Jia(Fenyang College of Shanxi Medical University,Fenyang 032200,China)
出处
《护理学杂志》
CSCD
北大核心
2023年第10期38-42,共5页
Journal of Nursing Science
基金
山西省研究生创新项目(2022Y438)
山西医科大学汾阳学院科研项目(2022C29)
山西省临床护理研究重点实验室项目(2020ZDSYS15)。
关键词
HER-2阳性
乳腺癌
双靶治疗
症状群
生活质量
相关性分析
HER-2 positive
Breast cancer
dual-target therapy
symptom clusters
quality of life
correlation analysis
