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联合门静脉结扎和肝脏分隔的二步肝切除术促进预留肝脏快速增生机制的研究进展

Research progress of accelerated liver regeneration induced by associating liver partition and portal vein ligation for staged hepatectomy
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摘要 联合门静脉结扎和肝脏分隔的二步肝切除术(ALPPS)可快速诱导剩余肝组织再生,为既往无法手术的肝癌患者提供了根治性切除的机会,被认为是本世纪肝脏外科领域具有突破性的进展之一。深入了解其作用机制对肝再生的相关研究具有十分重要的意义。本文就近年来全球有关ALPPS促进预留肝脏快速增生机制的研究进展作一综述。 Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)can induce accelerated regeneration of future liver remnant(FLR)and provide the opportunity of radical resection for previously inoperable patients with liver cancer,which has been considered to be one of the most important breakthroughs in liver surgery during the 21st century.It is of great significance to fully understand the mechanism of accelerated liver regeneration induced by ALPPS.This article comprehensively reviews the research progress in this field during the past 10 years.
作者 陈耿 陈穴 陈平 Chen Geng;Chen Xue;Chen Ping(Department of Hepatobiliary Surgery,Daping Hospital,Army Medical University,Chongqing 400042,China)
出处 《中华肝胆外科杂志》 CAS CSCD 北大核心 2023年第4期308-312,共5页 Chinese Journal of Hepatobiliary Surgery
基金 陆军军医大学科技创新能力提升专项(2019XLC1009) 陆军特色医学中心军事医学前沿创新能力培养计划(2019CXJSA003)。
关键词 肝再生 门静脉结扎 肝脏分隔 二步肝切除术 预留肝脏 Liver regeneration Portal vein ligation Liver partition Two-stage hepatectomy Future liver remnant
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