摘要
目的:探讨吉兰-巴雷综合征(GBS)临床特征对患者短期预后、呼吸衰竭的影响。方法:回顾性分析2015年1月—2020年12月锦州医科大学附属第一医院收治的61例GBS患者的临床资料,依据患者出院时Hughes评分分为短期预后良好组、短期预后不良组,同时根据患者呼吸状况分为呼吸衰竭组、无呼吸衰竭组,分析患者预后及合并呼吸衰竭的影响因素。结果:短期预后良好组入院Hughes评分、颅神经受累率、呼吸衰竭率均低于短期预后不良组;呼吸衰竭组前驱感染率、颅神经受累率、入院时Hughes评分高于无呼吸衰竭组,差异有统计学意义(P<0.05)。logistic回归分析显示,入院Hughes评分、颅神经受累、呼吸衰竭不是患者短期预后不良的影响因素(P>0.05);入院Hughes评分、颅神经受累是呼吸衰竭患者的影响因素(P<0.05)。结论:入院Hughes评分、颅神经受累是GBS患者伴呼吸衰竭的独立影响因素。
Objective:To explore the impact of clinical features of Guillain-Barre syndrome(GBS)on short-term prognosis and respiratory failure of patients.Methods:Clinical data of 61 GBS patients admitted to the First Affiliated Hospital of Jinzhou Medical University from January 2015 to December 2020 were retrospectively analyzed.According to Hughes score at discharge,the patients were divided into good short-term prognosis group and poor short-term prognosis group.According to the respiratory conditions of patients,the patients were also divided into respiratory failure group and non-respiratory failure group.The prognosis of patients and influencing factors of concurrent respiratory failure were analyzed.Results:The Hughes score at admission,cranial nerve involvement rate and respiratory failure rate in the good short-term prognosis group were lower than those in the poor short-term prognosis group;The prodromal infection rate,cranial nerve involvement rate and Hughes score at admission in the respiratory failure group were higher than those in the non-respiratory failure group,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that Hughes score at admission,cranial nerve involvement and respiratory failure were not influencing factors for poor short-term prognosis of patients(P>0.05).Hughes score at admission and cranial nerve involvement were influencing factors in patients with respiratory failure(P<0.05).Conclusion:Hughes score at admission and cranial nerve involvement are independent influencing factor of respiratory failure in GBS patients.
作者
彭珍妮
李健
Peng Zhenni;Li Jian(Jinzhou Medical University Graduate Training Base(Anshan Central Hospital),Anshan 114000,Liaoning Province,China;Department of Neurology,First Affiliated Hospital of Jinzhou Medical University,Jinzhou 121001,Liaoning Province,China)
出处
《中国社区医师》
2023年第13期26-28,共3页
Chinese Community Doctors
关键词
吉兰-巴雷综合征
呼吸衰竭
颅神经受累
Guillain-Barre syndrome
Respiratory failure
Cranial nerve involvement
