摘要
目的 探讨增强型体外反搏(EECP)应用于缺血性脑卒中恢复期患者,对神经功能、肢体肌力恢复及血清内皮素1(ET-1)水平的影响。方法 选择开封市中心医院康复治疗科2018-06-02-2020-06-02收治的123例缺血性脑卒中恢复期患者作为研究对象,按照随机数字表法分为对照组61例和观察组62例。对照组采用常规药物及康复干预,观察组在对照组基础上采用EECP干预,观察2组患者神经功能、肢体肌力水平、血清学指标及脑血流灌注情况。结果 干预后,观察组改良Rankin量表(mRS)评分为(2.20±0.54)分,低于对照组的(3.05±0.81)分,F=0.871,P=0.026;美国国立卫生研究院卒中量表(NIHSS)评分为(4.61±1.23)分,低于对照组的(8.82±1.08)分,F=15.055,P<0.001。干预后,观察组上肢肌力评分为(3.38±1.01)分,高于对照组的(2.86±0.73)分,F=4.963,P=0.028;下肢肌力评分为(3.38±1.02)分,高于对照组的(2.45±0.80)分,F=37.302,P<0.001。观察组血清ET-1水平为(50.12±8.56) pg/mL,低于对照组的(69.47±9.51) pg/mL,F=137.665,P<0.001;超敏C反应蛋白水平为(5.81±1.26) mg/L,低于对照组的(7.29±2.25) mg/L,F=10.494,P=0.002。观察组的脑血流灌注颈动脉阻力指数(RI)为0.67±0.02,低于对照组的0.76±0.04,F=267.506,P<0.001;平均流速(TMV)为(47.74±3.68) cm/s,高于对照组的(38.99±3.43) cm/s,F=48.355,P<0.001;收缩期峰值流速(PSV)为(62.21±5.05) cm/s,高于对照组的(58.44±5.13) cm/s,F=10.978,P=0.001。结论 EECP应用于缺血性脑卒中恢复期患者可有效改善血管内皮情况及脑血流灌注,提高神经功能及上下肢肌力。
Objective To investigate the effect of enhanced external counterpulsation(EECP) on neurological function, recovery of limb muscle strength and serum endothelin 1(ET-1) level in patients with ischemic stroke in convalescent period.Methods From June 2, 2018 to June 2, 2020 in Rehabilitation Treatment Department of Kaifeng Central Hospital, 123 patients with ischemic stroke in the recovery period were selected as the study subjects, and were divided into the control group(61 cases) and the observation group(62 cases) according to the random number table method. The control group was treated with routine drugs and rehabilitation intervention, while the observation group was treated with EECP intervention on the basis of the control group. The neurological function, limb muscle strength, serological indexes and cerebral blood flow perfusion of the patients in the two groups were observed.Results After the intervention, the modified Rankin scale(mRS) score of the observation group was 2.20±0.54, which was lower than that of the control group(3.05±0.81), F=0.871, P=0.026. The national institute of health stroke scale(NIHSS) score was 4.61±1.23, which was lower than that of the control group(8.82±1.08), F=15.055, P<0.001. After the intervention, the upper limb muscle strength score of the observation group was 3.38±1.01, which was higher than that of the control group(2.86±0.73), F=4.963, P=0.028. The lower limb muscle strength score was 3.38±1.02, higher compared with the control group(2.45±0.80), F=37.302, P<0.001. The serum ET-1 value of the observation group was(50.12±8.56) pg/ml, which was lower than that of the control group(69.47±9.51) pg/ml, F=137.665, P<0.001. The high-sensitivity C-reactive protein value was(5.81±1.26) mg/L, which was lower than that of the control group(7.29±2.25) mg/L, F=10.494, P=0.002. The resistance index(RI) value of cerebral blood perfusion in the observation group was 0.67±0.02,lower than that in the control group(0.76±0.04),F=267.506,P<0.001.The total mean velocity(TMV)va
作者
王晶晶
渠晶晶
杨俊涛
WANG Jingjing;QU Jingjing;YANG Juntao(Department of Rehabilitation Treatment,Kaifeng Central Hospital,Kaifeng 475000,China)
出处
《社区医学杂志》
CAS
2023年第7期357-361,共5页
Journal Of Community Medicine
关键词
增强型体外反搏
缺血性脑卒中
恢复期
神经功能
血流动力学
enhanced external counterpulsation
ischemic stroke
recovery period
neurological function
hemodynamics
