摘要
目的探讨出血性脑卒中急性期血压的动态变化、疾病史、用药情况与患者3个月死亡或mRS评分的关联情况。方法共收集106例急性出血性脑卒中患者,收集入院24 h内每6 h血压,第2-7天上午8点血压,最终取急性期10次收缩压(SBP)和舒张压(DBP)的均值、最大值、标准差和变异系数。利用Logistic回归模型分析基线血压及血压变化水平与3个月死亡或mRS评分的关系,利用Cox等比例风险模型计算各血压参数与死亡的关系。结果出血性脑卒中患者急性期收缩压和舒张压的均值及最大值与患者死亡和改良生活自理程度mRS评分有关,而急性期血压的变异系数和标准差与不良结局无关。结论出血脑卒中患者急性期血压升高与不良预后有关。
Objective To investigate the relationship between dynamic changes of blood pressure,disease history,medication and 3 months of death or mRS score in the acute stage of hemorrhagic stroke.Methods 106 patients with acute hemorrhagic stroke were enrolled in the study.Blood pressure at every 6 hours within 24 hours of admission and at 8 a.m.on days 2-7 were observed.The mean,maximum,standard deviation and coefficient of variation of SBP and DBP in the acute period were finally utilized.The relationship between blood pressure parameters and death or mRS score were analyzed by Logistic regression model,and the relationship between blood pressure parameters and death was calculated by using proportional risk models such as Cox.Results The mean and maximum values of acute systolic and diastolic blood pressure in patients with hemorrhagic stroke were related to the composite outcomes of the mRS score and death,while the coefficient of variation and standard deviation of blood pressure in the acute phase were not related to adverse outcomes.Conclusion Elevated blood pressure in the acute phase of patients with hemorrhage stroke is associated with poor prognosis.
作者
宋惠辉
罗欢
戴文卓
SONG Hui-hui;LUO Huan;DAI Wen-zhuo(Department of Neurology,Wuxi Second People's Hospital,Wuxi,Jiangsu,214002,China)
出处
《中国血液流变学杂志》
CAS
2022年第4期526-530,643,共6页
Chinese Journal of Hemorheology
关键词
出血性脑卒中
收缩压
舒张压
平均血压
预后
危险因素
hemorrhagic stroke
systolic blood pressure
diastolic blood pressure
mean blood pressure
prognosis
risk factor
