摘要
Osteoarthritis(OA),the most common joint disorder,was reported to affect 7%of the global population,and the number of people with OA has increased by almost 50%from 1990 to 2019[1].OA can occur in almost any moveable joint;however,the most commonly affected joints are the knee,hip,and hand.Pain,swelling,and stiffness are the most common clinical symptoms.
作者
魏捷
张余庆
David Hunter
曾超
雷光华
Jie Wei;Yuqing Zhang;David Hunter;Chao Zeng;Guanghua Lei(Department of Orthopaedics,Xiangya Hospital,Central South University,Changsha 410008,China;Health Management Center,Xiangya Hospital,Central South University,Changsha 410008,China;Department of Epidemiology and Health Statistics,Xiangya School of Public Health,Central South University,Changsha 410008,China;Hunan Key Laboratory of Joint Degeneration and Injury,Changsha 410008,China;Division of Rheumatology,Allergy,and Immunology,Department of Medicine,Massachusetts General Hospital,Harvard Medical School,Boston 02114,USA;The Mongan Institute,Massachusetts General Hospital,Harvard Medical School,Boston 02114,USA;Sydney Musculoskeletal Health,Kolling Institute,University of Sydney and Rheumatology Department,Royal North Shore Hospital,Sydney 2065,Australia;National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha 410008,China)
基金
supported by the National Key Research and Development Plan(2022YFC3601900 and 2022YFC2505500)
the National Natural Science Foundation of China(U21A20352)
the Project Program of National Clinical Research Center for Geriatric Disorders(2021LNJJ06)
the Natural Science Foundation of Hunan Province(2022JJ20100)。