摘要
目的探讨不同年龄及性别快动眼睡眠(REM)相关阻塞性睡眠呼吸暂停(OSA)患者的差异性。方法回顾性分析自2013年7月至2019年4月于北部战区总医院睡眠医学中心行整夜多导睡眠监测的227例REM相关OSA患者的临床资料。将患者根据年龄及性别分为年轻男性组(年龄≤44岁)、年轻女性组(年龄≤44岁)、年老男性组(年龄>44岁)及年老女性组(年龄>44岁)。收集患者年龄、性别、体质量指数(BMI)、睡眠结构参数、呼吸事件参数及血氧分布参数,比较4组患者在睡眠结构、呼吸事件、血氧分布方面的差异。结果4组患者的OSA严重程度、BMI比较,差异均无统计学意义(P>0.05)。年轻男性组总睡眠时间长于年老男性组,睡眠效率高于年老女性组,差异有统计学意义(P<0.05)。年老男性组N1睡眠长于年轻女性组和年老女性组,差异有统计学意义(P<0.05)。年老男性组N3睡眠、REM睡眠均短于年轻男性组、年轻女性组、年老女性组,差异有统计学意义(P<0.05)。年老男性组潜伏期N2、潜伏期N3均长于年老女性组,差异有统计学意义(P<0.05)。年老男性组REM-呼吸暂停低通气指数(AHI)、非快动眼睡眠(NREM)-AHI均高于年老女性组,差异有统计学意义(P<0.05)。年轻女性组平均血氧饱和度(SO_(2))高于年老男性组,SO_(2)<90%时间占监测总时间百分比低于年老男性组,差异有统计学意义(P<0.05)。结论不同年龄及性别REM相关OSA患者在睡眠结构、呼吸事件、血氧分布方面均存在显著差异,识别差异对个性化治疗及预后评价具有重要意义。
Objective To investigate the differences of rapid eye movement sleep(REM)-related obstructive sleep apnea(OSA)patients with different ages and genders.Methods The clinical data of 227 patients with REM-related OSA who underwent overnight polysomnography from July 2013 to April 2019 in the Sleep Medicine Center of General Hospital of Northern Theater Command were retrospectively analyzed.Patients were divided into young male group(age≤44 years old),young female group(age≤44 years old),old male group(age>44 years old)and old female group(age>44 years old)according to age and gender.Age,sex,body mass index(BMI),sleep structure parameters,respiratory events parameters and blood oxygen distribution parameters were collected,and the differences in sleep structure,respiratory events and blood oxygen distribution among the 4 groups were compared.Results There were no significant differences in OSA severity and BMI among 4 groups(P>0.05).The total sleep time of young male group was longer than that of old male group,and the sleep efficiency of young male group was higher than that of old female group,the difference was statistically significant(P<0.05).N1 sleep in the old male group was longer than that in the young female group and the old female group,and the difference was statistically significant(P<0.05).N3 sleep and REM sleep in the old male group were shorter than those in the young male group,young female group and old female group,and the difference was statistically significant(P<0.05).The incubation period N2 and N3 in the old male group were longer than those in the old female group,and the difference was statistically significant(P<0.05).The REM-apnea hypopnea index(AHI)and non-rapid eye movement sleep(NREM)-AHI in the old male group were higher than those in the old female group,and the difference was statistically significant(P<0.05).The average blood oxygen saturation(SO_(2))of young female group was higher than that of old male group,and the percentage of SO_(2)<90%in the total monitoring time was low
作者
褚金蒙
秦洁
闵英
吴大海
束美燕
闫洪琦
CHU Jin-meng;QIN Jie;MIN Ying;WU Da-hai;SHU Mei-yan;YAN Hong-qi(China Medical University,Shenyang 110001,China;Department of ENT&HN Surgery General Hospital of Northern Theater Command,Shenyang 110016,China)
出处
《临床军医杂志》
CAS
2023年第4期366-369,共4页
Clinical Journal of Medical Officers
基金
辽宁省科技攻关计划(2020JH2/10300171)。
