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有创-无创序贯通气联合肠内营养治疗ICU危重患者呼吸衰竭的疗效研究

Study on the Efficacy of Sequential Invasive-Noninvasive Mechanical Ven⁃tilation Combined with Enteral Nutrition in the Treatment of Respiratory Failure in Critically Ill Patients in ICU
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摘要 目的分析有创-无创序贯通气联合肠内营养治疗ICU危重患者呼吸衰竭的效果。方法回顾性选取2019年1月—2021年12月在盐城市第三人民医院围绕呼吸衰竭的ICU危重患者81例作回顾研究,样本按治疗方法进行分组,对照组(n=40)为有创序贯通气联合肠内营养,而观察组(n=41)为有创-无创序贯通气联合肠内营养,记录通气情况,进一步分析其血气指标、血流流变情况及心功能。结果观察组的有创通气时间(7.49±2.31)d、总机械通气时间(10.21±3.18)d,短于对照组,差异有统计学意义(t=10.052、6.425,P<0.05)。观察组在治疗后的动脉血二氧化碳分压显著低于对照组,而动脉血气酸碱值及动脉血氧分压更高,差异有统计学意义(P<0.05)。观察组在治疗后的全血黏度、血浆黏度及红细胞沉降率低于对照组,差异有统计学意义(P<0.05)。观察组的左室舒张末期内径及左心室收缩末期内径低于对照组,而左室射血分数更高,差异有统计学意义(P<0.05)。结论以有创-无创序贯通气联合肠内营养治疗ICU危重患者呼吸衰竭的疗效更好,其通气时间相对更短,对改善患者血气、血流流变及心功能相关指标均有重要意义。 Objective To analyze the effect of sequential invasive-noninvasive mechanical ventilation combined with enteral nutrition in the treatment of respiratory failure in critically ill patients in ICU.Methods 81 critical ICU pa⁃tients with respiratory failure in the Third People's Hospital of Yancheng City from January 2019 to December 2021 were selected for a retrospective study.The samples were grouped according to treatment methods.The control group(n=40)was treated with invasive sequential through gas combined with enteral nutrition,while the observation group(n=41)was treated with invasive and non-invasive sequential through gas combined with enteral nutrition,and the venti⁃lation was recorded.Blood gas index,blood flow and cardiac function were further analyzed.Results Invasive ventila⁃tion time(7.49±2.31)d and total mechanical ventilation time(10.21±3.18)d shorter in the observation group than in the control group,and the difference was statistically significant(t=10.052,6.425,P<0.05).Arterial blood carbon diox⁃ide partial pressure in the observation group being significantly lower than that in the control group after treatment,while the arterial blood gas acid-base values and arterial blood oxygen partial pressure were higher,and the difference was statistically significant(P<0.05).The whole blood viscosity,plasma viscosity and erythrocyte sedimentation rate in the observation group were lower than those in the control group after treatment,and the difference was statistically significant(P<0.05).The left ventricular end-diastolic internal diameter and left ventricular end-systolic internal diameter in the observation group were lower than those in the control group,while the left ventricular ejection fraction was higher,and the difference was statistically significant(P<0.05).Conclusion The combination of sequential invasive-noninvasive mechanical ventilation and enteral nutrition is more effective in the treatment of respiratory fail⁃ure in critically ill patients in ICU,and the ventilation time
作者 陈勇 张国培 张雨 CHEN Yong;ZHANG Guopei;ZHANG Yu(ICU,Yancheng Third People's Hospital,Yancheng,Jiangsu Province,224000 China)
出处 《中外医疗》 2023年第1期109-112,117,共5页 China & Foreign Medical Treatment
关键词 有创-无创序贯通气 肠内营养 ICU危重患者 呼吸衰竭 疗效 Sequential invasive-noninvasive mechanical ventilation Enteral nutrition ICU critically ill patients Respiratory failure Efficacy
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