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食药用菌多糖抗肿瘤机制的研究进展

Research Progress on Antitumor Mechanism of Polysaccharides from Edible and Medicinal Fungus
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摘要 肿瘤发病率逐年升高,对人类的危害不容忽视。天然活性物质食药用菌多糖提取工艺成熟,对机体毒副作用小,且具有较高的抗肿瘤药用价值。总结近十年来食药用菌多糖抗肿瘤机制的研究结果,分析了重要食药用菌的抗肿瘤特点、食药用菌抗肿瘤的调控机制及其功效,对多糖作为抗肿瘤纳米药物载体进行了阐述,对促进食药用菌多糖抗肿瘤应用的研究具有指导意义。 The incidence of cancer is increasing year by year,and the harm to human beings cannot be ignored.The natural active substance-edible and medicinal fungus polysaccharide possess mature extraction process,which has little toxic and side effects on the body and high anti-tumor medicinal value.This paper summarizes the research results of the anti-tumor mechanism of edible and medicinal fungus polysaccharide in the past ten years,analyzes the anti-tumor characteristics of important edible and medicinal fungus polysaccharide and anti-tumor efficacy,and expounds the use of polysaccharides as anti-tumor nano drug carrier.It has guiding significance for the research on promoting the anti-tumor application of edible and medicinal fungus polysaccharide.
作者 刘学娟 张洁 王晶 尚校兰 乔洁 李战永 常世民 闫训友 LIU Xue-juan;ZHANG Jie;WANG Jing(College of Life Sciences,Langfang Normal University,Langfang,Hebei 065000;Technical Innovation Center for Utilization of Edible and Medicinal Fungi in Hebei Province,Langfang,Hebei 065000;Langfang Key Laboratory of Cell Engineering and Application Research,Langfang,Hebei 065000)
出处 《安徽农业科学》 CAS 2023年第8期10-15,共6页 Journal of Anhui Agricultural Sciences
基金 国家自然科学基金青年科学基金项目(22203038) 2020年度河北省教育厅青年基金项目(QN2020255) 廊坊师范学院校级科研项目(XBQ202027)。
关键词 食药用菌多糖 肿瘤 调控机制 功效 Edible and medicinal fungus polysaccharide Tumor Manipulation mechanism Effect
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