摘要
卤化、氧化、重氮化、硝化以及催化加氢是精细化工生产中的重要反应,通常以间歇方式在釜式反应器中进行,存在安全隐患,并且反应效率低。微通道反应器技术的发展为解决上述问题提供了有效途径,因此,发展基于微通道反应器的安全高效合成工艺成为当前精细化工领域的研究热点之一。该文综述了近年来微通道反应器中涉及精细化工产品合成危险工艺的研究进展,并指出了微通道反应器存在的不足和今后研究的方向。
Halogenation,oxidation,diazotization,nitration and catalytic hydrogenation,which are important reactions in synthesis of fine chemicals,are generally carried out in batch reactors with low efficiency and potential safety hazards.The development of microchannel reactor technology provides an effective platform to solve the above problems.Therefore,safe and efficient synthetic processes in microchannel reactors become research focus in production of fine chemicals.Herein,the research progresses in the synthesis of fine chemicals involving hazardous processes in microchannel reactors in recent years were summarized,while the shortcomings and future research directions of microchannel reactor were also discussed.
作者
张家康
张月成
赵继全
ZHANG Jiakang;ZHANG Yuecheng;ZHAO Jiquan(School of Chemical Engineering and Technology,Hebei University of Technology,Tianjin 300131,China;Hebei Provincial Key Laboratory of Green Chemical Technology and High Efficient Energy Saving,Tianjin 300131,China;Tianjin Key Laboratory of Chemical Process Safety,Tianjin 300131,China)
出处
《精细化工》
EI
CAS
CSCD
北大核心
2023年第4期728-740,共13页
Fine Chemicals
基金
河北省生物医药联合基金重点项目(B2022202064)
中央引导地方科技发展资金项目(206Z4001G、216Z1401G)。