摘要
目的:观察鼻内镜中下鼻道联合开窗术治疗真菌性上颌窦炎患者的效果。方法:回顾性分析2019年12月至2020年10月该院收治的83例真菌性上颌窦炎患者的临床资料,按照手术方案不同将其分为观察组42例和对照组41例。观察组采用鼻内镜中下鼻道联合开窗术治疗,对照组采用鼻内镜中鼻道开窗术治疗,比较两组临床疗效、并发症发生率、复发率,术前、术后6个月鼻窦症状(Lund-Mackay)评分、嗅觉功能评分及术前、术后1 d血清炎性因子[肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白细胞介素-6(IL-6)、IL-1β]水平。结果:观察组治疗总有效率为95.24%(40/42),高于对照组的78.05%(32/41),差异有统计学意义(P<0.05);术后6个月,观察组Lund-Mackay评分低于对照组,嗅觉功能评分高于对照组,差异均有统计学意义(P<0.05);术后1 d,两组血清TNF-α、CRP、IL-6、IL-1β水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);术后6个月,观察组并发症发生率为2.38%(1/42),低于对照组的21.95%(9/41),复发率为5.00%(2/40),低于对照组的28.12%(9/32),差异均有统计学意义(P<0.05)。结论:鼻内镜中下鼻道联合开窗术治疗真菌性上颌窦炎患者可提高治疗总有效率和嗅觉功能评分,降低Lund-Mackay评分、血清炎性因子水平、并发症发生率和复发率,效果优于鼻内镜中鼻道开窗术治疗。
Objective:To observe effects of combined fenestration of middle and lower nasal meatus under nasal endoscope in treatment of fungal maxillary sinusitis.Methods:The clinical data of 83 patients with fungal maxillary sinusitis admitted to the hospital from December 2019 to October 2020 were retrospectively analyzed.According to different surgical schemes,they were divided into observation group(42 cases)and control group(41 cases).The observation group was treated with the combined fenestration of middle and lower nasal meatus under nasal endoscope,while the control group was treated with middle nasal meatus fenestration under nasal endoscope.The clinical efficacy,the incidence of complications,the recurrence rate,the sinus symptom(Lund-Mackay)score and the olfactory function score before and 6 months after the operation,and the inflammatory factor levels[tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6),IL-1β]before and 1 day after the operation were compared between the two groups.Results:The total effective rate of treatment in the observation group was 95.24%(40/42),which was higher than 78.05%(32/41)in the control group,and the difference was statistically significant(P<0.05).6 months after the operation,the Lund-Mackay score of the observation group was lower than that of the control group,the olfactory function score was higher than that of the control group,and the differences were statistically significant(P<0.05).1 day after the operation,the levels of serum TNF-α,CRP,IL-6 and IL-1βin the two groups were higher than those before the operation,but those in the observation group were lower than the control group,and the differences were statistically significant(P<0.05).Further,6 months after the operation,the incidence of complications in the observation group was 2.38%(1/42),which was lower than 21.95%(9/41)in the control group;the recurrence rate was 5.00%(2/40),which was lower than 28.12%(9/32)of the control group;and the differences were statistically significant(P<0.05).C
作者
孙晓伟
SUN Xiaowei(Department of Otolaryngology of Jiaozuo Wuguan Hospital,Jiaozuo 454000 Henan,China)
出处
《中国民康医学》
2023年第7期53-56,共4页
Medical Journal of Chinese People’s Health
关键词
鼻内镜
中下鼻道联合开窗术
中鼻道开窗术
真菌性上颌窦炎
嗅觉功能
并发症
炎性因子
Nasal endoscope
Combined fenestration of middle and lower nasal meatus
Middle nasal meatus fenestration
Fungal maxillary sinusitis
Olfactory function
Complication
Inflammatory factor
