摘要
Dear Editor,Nanotechnology-based therapeutic strategies have been proven effective in diseases including cancer,infection,inflammation,etc.1 However,the application of nanotechnology is greatly restricted in the treatment of central nervous system(CNS)disorders due to physiological CNS barriers.For example,the blood-brain barrier(BBB)can be the“Maginot line”for pharmacologically active molecules,blocking them out of the CNS.
基金
supported by grants from the National Key R&D Program of China(2019YFA0112000)
Zhejiang Provincial Natural Science Foundation of China(No.LQ21H300009)
National Natural Science Foundation of China(81930051,82003658,82202785)
GuangCi Professorship Program of Ruijin Hospital Shanghai Jiao Tong University School of Medicine.
