摘要
目的:分析尿石症患者的中医证候特征。方法:制定证候调查表,收集2021年9月至2022年9月就诊的296例尿石症患者的一般资料、四诊信息,统计舌象、脉象、症状体征,通过关联规则分析、因子分析和聚类分析探究证候特点。结果:(1)舌象分布中,出现频率在20%以上的单一舌象为白苔、红舌、厚苔、腻苔、黄苔。脉象分布中,出现频率>20%的单一脉象为细脉、弦脉、滑脉、沉脉。出现频率在10%以上的症状体征共27项,腰腹部疼痛及恶心、尿频、血尿、小便不畅等急性发作期特征症状相对较多,其余以寒热、二便和消化类症状较为常见。(2)14条强关联规则中,5条为阳虚、寒湿类证候表现,4条为阴虚、热证类证候表现,1条为肾虚类证候表现,3条为肾绞痛及伴随症状。(3)因子分析共提取16个公因子,代表的病位证候要素以脾肾为主,病性证候要素以阴虚、阳虚、湿、热为主,并常见虚实夹杂。聚类分析共获得6类证候,代表的主要证型分别为肾虚湿瘀、气滞热结、阴虚湿热、脾肾阳虚、脾虚湿热、湿热内蕴。结论:尿石症患者证候表现以寒热、二便、汗出和消化道症状常见,虚证类证候主要为阴虚、阳虚、肾虚、脾虚,实证类证候主要为湿、热,虚实类证候常相兼存在,脾虚是当前尿石症患者除肾虚外的重要病机。
Objective:To analyze the characteristics of tradition Chinese medicine(TCM)syndromes in patients with urolithiasis.Method:A syndrome questionnaire was developed to collect the general data and four diagnosis information on 296 patients with urolithiasis who were treated from September 2021 to September 2022.Tongue images,pulse images,symptoms,and signs were statistically analyzed,and the characteristics of syndrome were explored by association rule analysis,factor analysis,and cluster analysis.Result:①In the distribution of tongue images,the single tongue images with a frequency of more than 20%were white fur,red tongue,thick fur,greasy fur,and yellow fur.In the distribution pf pulse images,the single pulse with the frequency of more than 20%was fine pulse,string pulse,slippery pulse,and sinking pulse.There were 27 symptoms and signs with a frequency of more than 10%.The characteristic symptoms of acute onset such as lumbar and abdominal pain and nausea,frequent urination,hematuria,and poor urination were relatively common,and other symptoms were chill and fever,defecation,and digestion.②Among the 14 strong association rules,5 were yang-deficiency and cold-dampness syndromes,4 were yin-deficiency and heat syndromes,1 was kidney-deficiency syndrome,and 3 were renal colic with accompanying symptoms.③Sixteen common factors were extracted by factor analysis,and the main elements of the disease location were represented by spleen and kidney.The main elements of disease natures were Yin deficiency,Yang deficiency,dampness,and heat,and often mixed with deficiency-excess in complexity.Six syndromes were obtained by cluster analysis,and the represented syndromes were mainly kidney deficiency and dampness and stasis,Qi stagnation and heat accumulation,Yin deficiency and dampness heat,spleen-kidney Yang deficiency,spleen deficiency and dampness,and dampness-heat accumulation.Conclusion:The syndrome manifestations of urolithiasis are chill and fever,defecation,sweating,and digestive tract symptoms.The deficiency syndro
作者
刘菡
张耀圣
LIU Han;ZHANG Yaosheng(Dongzhimen Hospitial,Beijing University of Chinese Medicine,Beijing 100700,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2023年第10期209-215,共7页
Chinese Journal of Experimental Traditional Medical Formulae
基金
北京中医药“薪火传承3+3工程”项目。
关键词
尿石症
证候要素
证候特征
数据挖掘
urolithiasis
syndrome elements
syndrome characteristics
data mining
