摘要
目的:分析原发性肝癌疾病特点,评价C型臂下肝动脉灌注化疗栓塞治疗的可行性和临床疗效。方法:选择2018年8月~2020年1月本院诊治的84例原发性肝癌疾病患者,采取随机法进行对照组、观察组分组治疗,各42例。对照组采取华蟾素/康莱特等保守治疗,观察组采取C型臂下肝动脉灌注化疗栓塞治疗。比较2组临床疗效、生命质量以及血清肿瘤坏死因子-α、血管内皮生长因子、碱性成纤维细胞生长因子水平。生命质量以健康调查简表(SF-36)评估。结果:临床疗效方面比较,观察组原发性肝癌患者的治疗总有效率(88.09%)高于对照组(47.61%),P<0.05;生命质量评分方面,观察组原发性肝癌患者治疗后评分(88.30±5.50)分明显高于治疗前评分(73.20±4.50)分,P<0.05;血清肿瘤坏死因子-α、血管内皮生长因子、碱性成纤维细胞生长因子水平比较,观察组均优于对照组,P<0.05。结论:对比保守治疗,C型臂下肝动脉灌注化疗栓塞治疗原发性肝癌效果理想,提高了患者的生存质量,是优选治疗方法。
Objective:To analyze the characteristics of primary liver cancer and evaluate the feasibility and clinical efficacy of C-type inferior hepatic artery infusion chemoembolization.Methods:84 patients with primary liver cancer diagnosed and treated in our hospital from August 2018 to January 2020 were randomly divided into a control group and an observation group for treatment,with 42 patients in each group.The control group received conservative treatment such as Huachansu/Kanglaite,while the observation group received C-type subabdominal hepatic artery infusion chemotherapy embolization treatment.Compare the clinical efficacy,quality of life,and serum tumor necrosis factor between two groups-α,Levels of vascular endothelial growth factor and basic fibroblast growth factor.The quality of life is evaluated using the Health Survey Short Form(SF-36).Results:In terms of clinical efficacy,the total effective rate of primary liver cancer patients in the observation group(88.09%)was higher than that in the control group(47.61%),P<0.05;In terms of quality of life score,the postoperative score(88.30±5.50)of patients with primary liver cancer in the observation group was significantly higher than the preoperative score(73.20±4.50),P<0.05;Serum tumor necrosis factor-α,the comparison of levels of vascular endothelial growth factor and basic fibroblast growth factor showed that the observation group was better than the control group,P<0.05.Conclusion:Compared with conservative treatment,C-type inferior hepatic artery infusion chemoembolization in the treatment of primary liver cancer has an ideal effect and improves the patient’s quality of life.It is the preferred treatment method.
作者
李雯
LI Wen(Department of Gastroenterology and Hematology,Donggang Central Hospital,Liaoning Donggang 118300)
出处
《中国医疗器械信息》
2023年第7期95-97,共3页
China Medical Device Information
关键词
C型臂下肝动脉灌注化疗栓塞
保守治疗
原发性肝癌
治疗效果
生存质量
C-type inferior hepatic artery infusion chemoembolization
conservative treatment
primary liver cancer
treatment effect
quality of life
