摘要
目的分析肺癌患者术后住院期间发生肺栓塞的危险因素。方法收集2019年3月至2022年5月于首都医科大学附属北京同仁医院收治的90例肺癌患者的临床资料,根据术后住院期间是否发生肺栓塞将患者分为栓塞组和对照组,每组45例。分析肺癌患者术后住院期间发生肺栓塞的危险因素。结果栓塞组术前D-二聚体水平、术前C反应蛋白水平、TNM分期为Ⅲ~Ⅳ期的患者比例、术中出血量均高于对照组,手术时间长于对照组,差异均有统计学意义(P<0.05)。多因素分析结果显示,术前D-二聚体水平升高、术前C反应蛋白水平升高、TNM分期为Ⅲ~Ⅳ期、手术时间>3 h和术中出血量>200 ml均是肺癌患者术后住院期间发生肺栓塞的独立危险因素(P<0.05)。结论术前D-二聚体平、术前C反应蛋白水平、TNM分期、手术时间和术中出血量均与肺癌患者术后住院期间发生肺栓塞密切相关,术前应注意筛查存在这些因素的高危患者,做好针对性预防。
Objective To analyze the risk factors associated with pulmonary embolism in patients with lung cancer during postoperative hospitalization.Method The clinical data of lung cancer patients admitted to Beijing Tongren Hospital,Capital Medical University from March 2019 to May 2022 were collected,the patients were divided into embolization group and control group based on whether pulmonary embolism occurred during postoperative hospitalization,with 45 cases in each group.The risk factors for pulmonary embolism during postoperative hospitalization in patients with lung cancer were analyzed.Result The preoperative D-dimer level,preoperative C-reactive protein level,proportion of patients with TNM stage III-IV and the intraoperative blood loss in the embolization group were higher than those in the control group,the operation time was longer than that in the control group,and the difference were statistically significant(P<0.05).The results of multivariate analysis showed that the preoperative D-dimer level was increased,the preoperative C-reactive protein level was increased,the TNM stage was stage III-IV,the operation time was>3 h,and the intraoperative blood loss was>200 ml were independent risk factors for pulmonary embolism during postoperative hospitalization in patients with lung cancer(P<0.05).Conclusion Preoperative D-dimer level,preoperative C-reactive protein level,TNM stage,operation time,and intraoperative blood loss were all closely related to the occurrence of pulmonary embolism during postoperative hospitalization of lung cancer patients,preoperative attention should be paid to screening high-risk patients with these factors and targeted prevention should be taken.
作者
黑晓欢
张葆勋
翟梦芳
王小飞
Hei Xiaohuan;Zhang Baoxun;Zhai Mengfang;Wang Xiaofei(Department of Thoracic Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100005,China)
出处
《血管与腔内血管外科杂志》
2023年第3期300-303,314,共5页
Journal of Vascular and Endovascular Surgery
关键词
肺癌
手术
肺栓塞
危险因素
预防
lung cancer
operation
pulmonary embolism
risk factor
prevention
