摘要
目的:观察耳背静脉放血联合耳穴贴压治疗气滞血瘀型月经性偏头痛(MM)的临床疗效,探讨其可能作用机制.方法:将102例气滞血瘀型MM患者随机分为观察组(51例,脱落3例)和对照组(51例,脱落2例).观察组予耳背静脉放血联合耳穴贴压治疗,于耳背上1/3近耳轮处充盈的静脉进行放血,于皮质下、内分泌、交感、颞、枕、神门、胰胆进行贴压,双耳交替,从月经来潮前7 d开始,耳背静脉放血每7天1次,3次为一疗程,共治疗1个疗程,耳穴贴压每3天1次,共治疗6次;对照组予口服盐酸氟桂利嗪胶囊治疗,从月经来潮前7 d开始,每次2粒,每日1次,连续治疗3周.观察两组患者治疗前、治疗1个月经周期后及治疗后第1、2个月经周期头痛指数、视觉模拟量表(VAS)评分,比较两组患者治疗前、治疗1个月经周期后偏头痛特异性生活质量问卷(MSQ)评分及血清雌二醇(E_(2))、5-羟色胺(5-HT)含量,于治疗1个月经周期后评定临床疗效.结果:治疗1个月经周期后及治疗后第1、2个月经周期,两组患者头痛指数、VAS评分均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05).治疗1个月经周期后,两组患者MSQ评分及血清E_(2)、5-HT含量均较治疗前升高(P<0.05),且观察组高于对照组(P<0.05).观察组总有效率为95.8%(46/48),高于对照组的73.5%(36/49,P<0.05).结论:耳背静脉放血联合耳穴贴压治疗气滞血瘀型MM可缓解头痛强度,改善患者生活质量,可能是通过上调血清E_(2)、5-HT含量,改善体内激素水平实现的.
Objective To observe the clinical effect of bloodletting at auricular dorsal vein combined with auricular point sticking on menstrual migraine(MM)of qi stagnation and blood stasis,and explore its possible mechanism.Methods A total of 102 cases of MM with qistagnation and blood stasis were randomly divided into an observation group(51 cases,3 cases dropped f)and a control group(51 cases,2 cases dropped off).The patients in the observation group were treated with bloodletting at auricular dorsal vein combined with auricular point sticking.The bloodletting was performed at vein at upper 1/3 of the dorsalis near the ear helix;the auricular point sticking was performed at Pizhixia(AT_(4)),Neifenmi(CO_(18)),Jiaogan(AH_(60)),Nie(AT_(2)),Zhen(AT_(3)),Shenmen(TF_(4))and Yidan(CO_(11)).The auricular points of both ears were alternate used.From 7 days before the onset of menstruation,bloodletting at auricular dorsal vein was given once every 7 days,3 times were taken as a course of treatment,and I course of treatment was given;the auricular point sticking was given once every 3 days,and 6 times of treatment were given.The patients in the control group were treated with oral administration of flunarizine hydrochloride capsules.From 7 days before the onset of menstruation,flunarizine hydrochloride was given 2 capsules per time,once a day for 3 weeks.The menstrual headache index and visual analogue scale(VAS)score of the two groups were observed before treatment,one menstrual cycle into treatment and the first and the second menstrual cycle after treatment;the migraine-specific quality of life questionnaire(MSQ)score and the serum levels of estradiol(E_(2))and 5-hydroxytryptamine(5-HT)were compared before treatment and one menstrual cycle into treatment;the clinical efficacy was evaluated at one menstrual cycle into treatment.Results Compared before treatment,the menstrual headache index and VAS scores were reduced at one menstrual cycle into treatment and the first and second menstrual cycle after treatment in the two groups(
作者
李瑞
卢岩
王萌萌
杨佃会
LI Rui;LU Yan;WANG Meng-meng;YANG Dian-hui(School of Acupuncture-Moxibustion and Tuina,Shandong University of TCM,Jinan 250355,China;Department of Acupuncture and Moxibustion,Affiliated Hospital of Shandong University of TCM,Jinan 250014;Heritage Studio of National Famous Doctors of TCM SHAN Qiu-hua,Jinan 250014,Shandong Province)
出处
《中国针灸》
CAS
CSCD
北大核心
2023年第4期427-431,436,共6页
Chinese Acupuncture & Moxibustion
基金
山东省自然科学基金青年项目:ZR2020QH315
山东省中医药科技项目:Z-2022095T
齐鲁医派中医学术流派传承项目:鲁卫函【2020】132号。
关键词
月经性偏头痛
耳背静脉放血
耳穴贴压
雌二醇
5-羟色胺
随机对照试验
menstrual migraine
bloodletting at auricular dorsal vein
auricular point sticking
estradiol(E_(2))
5-hydroxytryptamine(5-HT)
randomized controlled trial(RCT)
